Unit:
Τομέας Υγείας - Μητέρας - ΠαιδιούLibrary of the School of Health Sciences
Author:
Τσουβαλάς Εμμμανουήλ
Dissertation committee:
Αναπληρώτρια Καθηγήτρια Καραβανάκη Κυριακή-Αθηνά
Original Title:
Συσχέτιση του πάχους του έσω-μέσου χιτώνα των καρωτίδων με παράγοντες προφλεγμονώδους διεργασίας σε παιδιά με σακχαρώδη διαβήτη τύπου 1
Translated title:
Correlation of carotid intima-media thickness with proinflammatory factors in children with diabetes mellitus type 1
Summary:
Type 1 diabetes (T1D) is a generally accepted atherogenic risk factor. Carotid
intima media thickness (CIMT) is considered as an early marker of subclinical
atherosclerosis in patients with Τ1D. However, there are limited relevant
studies in children and adolescents with T1D, with conflicting results.
Moreover, factors OPG/RANKL, which are markers of bone turnover, have been
successfully evaluated as surrogate biomarkers of early cardiovascular disease,
in limited studies on adult patients with T1D or T2D, while there is no
relative previous study in childhood diabetes.
Keywords:
Diabetes mellitus type 1, Carotid intima-media thickness, Children and adolescents, Osteoprotegerin, RANKL
Number of references:
234