Summary:
In our prospective study, the eyes of 140 Greek patients with acute (112 eyes)
or chronic (38 eyes) central serous chorioretinopathy (CSC) with regard to
their specific clinical characteristics as well as the efficacy of photodynamic
therapy (PDT) were studied. PDT was applied based on fluorescein angiography
with small and if necessary, multiple spots directly on the leaking points and
RPE decompensations. According to our results, this method of treatment seems
to be effective and safe. It is more advantageous over PDT which is applied
based on indocyanine green angiography (a single large spot) since the
treatment was applied to a wide area of the posterior pole which can lead to
several anatomical or functional disorders even when PDT is applied with
modified techniques. The disadvantage of the FA guided multiple small spots
technique can be the difficulty in precisely locating the leaking points where
the PDT should be applied. However, this can be solved through mapping of the
spots which the ophthalmologist uses as a guide during the PDT procedure in
order to have adequate points to achieve an accurate application.