Τομέας ΙΙΙ [Ανόργανη Χημεία – Ανόργανη Χημική Τεχνολογία – Περιβαλλοντική Χημεία]
Library of the School of Science

2015-10-16

2015

Χαλκιαδάκη Όλγα

Εμμανουήλ Δασενάκης Καθηγητής (επιβλέπων), Αθανάσιος Βαλαβανίδης Καθηγητής, Νικόλαος Λυδάκης-Σημαντήρης Αναπληρωτής Καθηγητής

Αλληλεπίδραση βαρέων μετάλλων και πρωτεϊνών σε θαλάσσιους βενθικούς οργανισμούς

Greek

Heavy metals and proteins interactions in marine benthic organisms

This Thesis aims to study the effect of heavy metals in benthic organisms and
particularly the development of their defense mechanisms. During its
implementation, experiments were performed with different organisms (Mytilus
galloprovincialis, Callista chione, Venus verrucosa) which were collected from
their natural environment, cultivated in aquariums under controlled conditions
and then exposed to high concentrations of heavy metals (Pb, Cd, Ni). Their
bioaccumulation was determined in the gills, mantle, digestive system and body.
Isolation and identification of proteins induced by heavy metals in these
tissues followed. Perhaps, the most important defense mechanism of the exposed
organisms was the expression of large amounts of metallothioneins. In addition,
it was found that under these conditions of stress, cells overexpressed or
inactivated enzymes that normally help in cells’ function. The levels of lipid
peroxidation, acetylcholinesterase, glutathione S transferase, glutathione
reductase and catalase were studied. It was found that metallothionein, enzyme
and lipid peroxidation levels depend on the type of metal, the exposure
concentration, the duration of exposure and the tissue under study.

Marine bivalves, Heavy metals, Bioaccumulation, Biomarkes

Yes

1-10

Yes

398

323

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https://pergamos.lib.uoa.gr/uoa/dl/object/1308623