Development of Mass Spectrometric Methods for the determination of Emerging Pollutants in wastewater

Doctoral Dissertation uoadl:1309603 707 Read counter

Unit:
Τομέας Ι [Θεωρητική Χημεία – Φυσικοχημεία – Ανόργανη Ανάλυση – Ενόργανη Ανάλυση – Οργανολογία – Χημική Μηχανική (Εφαρμ. Φυσικοχημεία)]
Library of the School of Science
Deposit date:
2015-10-21
Year:
2015
Author:
Μπλέτσου Άννα
Dissertation committee:
Νικόλαος Θωμαΐδης Αναπλ. Καθηγητής
Original Title:
Development of Mass Spectrometric Methods for the determination of Emerging Pollutants in wastewater
Languages:
English
Translated title:
Ανάπτυξη Μεθόδων Φασματομετρίας Μάζας για τον προσδιορισμό Αναδυόμενων Ρύπων σε υγρά απόβλητα
Summary:
The presence of emerging pollutants in environmental samples is unquestionable,
since urban, industrial and agricultural activities release in the aquatic
environment great amounts of diverse organic micropollutants over the last
decade. Environmental monitoring is an urgent nowadays, as a part of a holistic
environmental risk assessment. The main objective of this thesis was the
development of highly sensitive methods for the determination of multi-class
emerging pollutants with the use of different mass spectrometric techniques.
First, an introduction on the emerging pollutants is presented, since they
encompass a diverse group of compounds, highlighting their wide-scope
properties. Specific workflows and techniques for their determination are then
presented, focusing in target and suspect screening by mass spectrometric
techniques and especially in the development of high-resolution mass analyzers.
The experimental section of the thesis consists of three parts: (i)
Determination of Linear and Cyclic Siloxanes by gas chromatography hyphenated
with mass spectrometry in environmental samples and evaluation of Mass Loadings
and Fate in a Wastewater Treatment Plant in Greece (Chapter 3), (ii) Wide-scope
quantitative target screening of 2327 emerging contaminants in wastewater
samples with Ultra-Performance Liquid Chromatography Quadrupole-Time-Of-Flight
Mass Spectrometry (UPLC-Q-ToF-HRMS/MS) (Chapter 4) and (iii) Suspect screening
workflow for the characterization of emerging polar organic contaminants in
wastewater samples with Ultra-Performance Liquid Chromatography High-Resolution
Mass Spectrometry (UPLC-HRMS/MS) (Chapter 5).
It is our strong belief that these studies will constitute a step forward in
environmental analysis of emerging pollutants.
Keywords:
Emerging pollutants, LR-MS, HR-MS, target screening, environmental samples
Index:
Yes
Number of index pages:
1-11
Contains images:
Yes
Number of references:
218
Number of pages:
202
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