Dissertation committee:
Δασενάκης Εμμανουήλ Καθηγητής (Επιβλέπων), Μπακέας Ευάγγελος Αναπλ. Καθηγητής, Λεοντιάδης Λεόντιος Ερευνητής Α΄
Summary:
The presence of emerging environmental pollutants, like perfluoroalkylated
substances (PFASs) in food products is one of the main issues for food safety.
However, risk assessment of the dietary exposure to PFASs is hampered by the
insufficient available information and thus further investigation is needed.
Thus, the main objective of this study is the risk assessment of PFASs through
their detection in different food matrices, drinking water and food packaging
materials. In the present study, both direct and indirect ways of food
contamination were examined and evaluated. Human exposure to PFASs via the
consumption of certain food items was also estimated. In order to detect very
low levels of PFASs in all the aforementioned matrices, sensitive and selective
analytical methods were developed.
The current thesis, apart from the development of novel analytical methods
comprises of five distinct parts: (1) Determination of PFASs in various
foodstuff packaging materials used in the Greek market, (2) Levels of PFASs in
raw and cooked Mediterranean finfish and shellfish, (3) PFASs in home and
commercially produced chicken eggs from the Netherlands and Greece, (4)
Determination of PFASs in drinking water from the Netherlands and Greece, (5)
PFASs in edible livers of farm animals, including accumulation kinetics in
young sheep fed with contaminated feed.
Keywords:
Perfluoroalkylated substances , Food , Drinking water, Food packaging materials, LC-MS/MS