Κατεύθυνση Παθολογία της Κύησης
Library of the School of Health Sciences

2016-04-06

2016

Χούλης Φανούριος

Καθηγητής Νικόλαος Παπαντωνίου, Ομότιμος Καθηγητής Δημήτριος Κασσάνος, Ομότιμος Καθηγητής Εμμανουήλ Σαλαμαλέκης

Αντιπηκτική αγωγή και έκβαση της κύησης σε ασθενείς με Θρομβοφιλία

Greek

Anticoagulant treatment and pregnancy outcomes in patients with Thrombophilia

Physiological changes during pregnancy in the coagulation and fibrinolytic
systems create a “natural hypercoagulable state”. This pro-coagulant state
entails an increased risk of thromboembolism and could also expose a woman to
the occurrence of complications and adverse pregnancy outcomes, especially in
the presence of acquired or inherited thrombophilia through a thrombotic
process or through inflammatory and other partially known processes. Scope of
this review is to address the best possible approach for diagnosis, prevention
and treatment of pregnancy complications and adverse pregnancy outcomes in
women with thrombophilia. A literature search, from January 2006 to February
2016, with specific search strategy, was conducted. The following search terms
were used and combined: thrombophilia AND pregnancy outcomes OR pregnancy
complications AND anticoagulant. Aspirin is efficacious in the prevention of
gestational vascular complications in women at risk for pre-eclampsia and in
those with antiphospholipid antibodies.Heparins could give benefit to women at
risk for early onset and/or severe gestational vascular complications (early
onset pre-eclampsia, severe placenta abruption, small for gestational age
newborn < 5th percentile, or late pregnancy loss > 20 weeks of gestation)and/or
pregnancy-related Venous Thromboembolism but future studies should be conducted
and may shed further light on this possibility.

Thrombophilia, Pregnancy, Pregnancy complications, Pregnancy outcome, Anticoagulant treatment

Yes

3-8

Yes

201

200

File access is restricted.

https://pergamos.lib.uoa.gr/uoa/dl/object/1310112