Κατεύθυνση Εργαστηριακή και Κλινική Νοσηλευτική ΚαρδιολογίαLibrary of the School of Health Sciences
Φιλιππάτος Γεράσιμος, Αναπληρωτής καθηγητής
Εκτίμηση της ποιότητας ζωής των ενηλίκων ασθενών με συγγενείς καρδιοπάθειες με τον δείκτη δραστηριότητας Duke
Purpose. The purpose of the study was to assess the quality of life of
adult patients with congenital heart disease according to the Duke Activity
Status Index and to evaluate the prognostic significance of the index.
Method. The population of the study consisted of a total of 76 consecutive
patients with congenital heart disease, who were examined at the regular
practice of congenital heart disease or were hospitalized at the 2nd university
cardiology clinic of the 'Attikon' University General Hospital. The patients
had simple , complex or cyanotic congenital heart disease Out of a total of 76
patients, 70 replied to the Duke questionnaire and were therefore included in
Results. In this research paper, we studied the admission for hospital
management, the cardiovascular outcomes and the worsening of symptoms of our
patients according to NYHA and how the above are associated with the Duke
When the patients were divided into those who presented any major
cardiovascular outcome or death, the survival analysis (cox regression
analysis) showed that lower Duke values :
Were related to an increased risk (HR= 0.956) for hospital admission (CI 95% =
Were linked with an increased risk (HR= 0.920) for worsening of the symptoms
according to NYHA with (CI 95 % = 0.847-1.000, p= 0.049).
Were linked with an increased risk (HR= 0.968) for cardiovascular outcomes (CI
95 % = 0.940-0.997, p= 0.029).
Discussion . Based on studies, the Duke index has prognostic significance in
patients with heart failure. This study showed that the Duke index is affected
in patients with congenital heart
Conclusions. Duke is affected in patients
with congenital heart disease and may have a prognostic value for these
Quality of life, Congenital heart disease, Heart failure, Duke activity status index, Capacity of exercise
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