Summary:
Ovariohysterectomy in female dogs is one of the most common surgical procedures
in veterinary medicine.
Thromboelastometry is a global assay that reflects the overall coagulation
status. Recently, Rotem has been validated for use in veterinary medicine and
it is used more often to assess the risk of hemorrhage or thrombosis and to
monitor the anticoagulant medications therapy.
Our study included 15 healthy female dogs before, during and one hour after
ovariohysterectomy. The purpose of this thesis is to define the normal range of
thromboelastometry values perioperatively, and to investigate the hemostatic
response to surgery and anesthesia.
Results were recorded of the Clot Time, the Clot Formation Time, the Alpha
angle, the Maximum Clot Firmness, the Amplitude at 5, 10, 15, and 20 minutes,
the Clot Lysis LY60, the Prothrombine Time, the activated Partial
Thromboplastin Time, and finally Fibrinogen concentration. Complete blood
counts were performed and serological assays for infectious diseases (Ehrlichia
canis and Leishmania infantum).
The statistical analysis of the data did not demonstrate the multivariate
normal distribution. Clot Time and Clot Formation Time were higher one hour
post operationally, but only for the CT there was a statistically significant
elevation. Furthermore, there is a strong positive correlation between
hematocrit and both prothrombine time and fibrinogen.
The data from our study revealed that there were no significant alterations in
the coagulation status of healthy dogs, perioperatively.
Keywords:
TEG, ROTEM, Canine, Coagulation, Ovarianhysterectomy
