Unit:
Κατεύθυνση Έρευνα στην Γυναικεία ΑναπαραγωγήLibrary of the School of Health Sciences
Author:
Αναγνωστοπούλου Καλλιόπη
Supervisors info:
Αναπληρώτρια Καθηγήτρια Σταυρούλα Μπάκα, Αναπληρωτής Καθηγητής Δημήτριος Χασιάκος, Αλέξανδρος Γρυπάρης PhD
Original Title:
Eπίπεδα βισφατίνης στο σπερματικό πλάσμα
Translated title:
Visfatin levels on seminal plasma
Summary:
Visfatin was discovered many years ago as nicotinamide
phosphoribosyltransferase (NAMPT), which is involved in nicotinamide adenine
dinucleotide (NAD) biosynthesis. NAMPT was rediscovered a few years later as
PBEF1 (pre-B cell colony-enhancing factor), a cytokine that plays an important
role in pre-B lymphocytes maturation. Later on, visfatin was found in the
adipose tissue as an adipocytokine with a strong insulin-mimetic effect. The
aim of this study is to detect visfatin on human seminal plasma and to
investigate a possible correlation between visfatin and the characteristics of
spermatozoa (concentration, motility, morphology). The results of this study
were the detection of visfatin on human seminal plasma and a mildly negative
correlation between visfatin and sperm concentration, as well as to the total
number of spermatozoa. In concusion, visfatin might play a small role in
spermatogenesis but further research is required.
Keywords:
Visfatin, Seminal plasma, Spermatozoa motility , Spermatozoa concentration, Spermatozoa morphology
