Unit:
Κατεύθυνση Κλινικοπαθολογοανατομική θεώρηση των νεοπλασιών του ανθρώπουLibrary of the School of Health Sciences
Supervisors info:
Αναπληρώτηρια Καθηγήτρια Εύη Kαΐρη-Βασιλάτου
Original Title:
Kλινικοπαθολογοανατομικά χαρακτηρηστικά μεταστατικών ωοθηκικών όγκων
Summary:
Ovarian cancer is the most dangerous neoplasia of the genital tract. Its
prevalence is 6% in the western world and it is the leading cause of death from
cancer in the gynecological system. This is a retrospective study including 108
patients with pathological diagnosis of metastatic ovarian neoplasms, examined
during the decade 2000–2013. The gross, microscopical and immunohistochemical
characteristics as well as the clinical data (age of the patients, origin of
the neoplasm, symptoms, treatment options) were examined. The mean age of the
patients is 55 years (range26–78 years). 68,51% of the tumors were metastatic
from extragenital organs (from stomach 24,07%, breast 14.81% colon 20.37%,
appendix 0.92%, pancreas 1.85%, lung 0.92% kidney 0.92%, sarcoma 0.92% melanoma
0.92%) 31.48% of the tumors originated from the genital tract. The management
of metastatic ovarian neoplasms should include specific immunohistochemical
methods in order to identify the primary neoplasm site. Tumor
immunohistochemistry is a helpful aid in the differential diagnosis mainly
between primary mucinous ovarian tumors and metastatic colon cancers and in the
recognition of metastatic breast cancers and other neoplasms of the GI tract.
Keywords:
Μetastatic cancer, Ovary, Ovarian neoplasms
Number of references:
151
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