Method development for the recovery and the isolation of sesamin and sesamolin from sesame oil

Postgraduate Thesis uoadl:1315848 473 Read counter

Unit:
ΠΜΣ με ειδίκευση ΑΠΟΜΟΝΩΣΗ, ΑΝΑΠΤΥΞΗ, ΠΑΡΑΓΩΓΗ ΚΑΙ ΕΛΕΓΧΟΣ ΒΙΟΔΡΑΣΤΙΚΩΝ ΦΥΣΙΚΩΝ ΠΡΟΪΟΝΤΩΝ
Library of the School of Science
Deposit date:
2015-11-18
Year:
2015
Author:
Μιχαηλίδης Δημήτριος
Supervisors info:
Αλέξιος-Λέανδρος Σκαλτσούνης Καθηγητής
Original Title:
Ανάπτυξη διαδικασίας για την παραλαβή και απομόνωση της σησαμίνης και της σησαμολίνης από το σησαμέλαιο
Languages:
Greek
Translated title:
Method development for the recovery and the isolation of sesamin and sesamolin from sesame oil
Summary:
Sesame oil is a highly important product directly linked to the cultural
heritage of Asian and African people for more than 5000 years. Nowadays, its
importance for these cultures is similar as the importance of olive oil in
Mediterranean countries. In 2013 the global production exceeded the amount of
one million tons to meet market needs, that bear substantiates the widespread
use. The timeless consumption has attracted scientific interest for decades,
leading to study both the recommendation and the action of secondary
metabolites.
Sesame oil is produced from the seeds of the plant Sesamum indicum L.
and characterized by a high concentration of lignans. The main lignans found in
oil, are sesamin and sesamolin molecules with important pharmacological effects
and intense economic interest.
The aim of this study is the development of isolation method, for those
two lignans, using techniques applicable in industrial level. To conduct the
experimental procedure it was necessary to occur curves quantification for each
compound. Firstly, a multitude of extraction systems was tested. Then, the
appropriate system was applied to a number of different extraction techniques.
Specifically, four extraction methods were compared. Finally, sesamin and
sesamolin isolated by using countercurrent chromatography.
Keywords:
Sesamin, Sesamolin, Sesame oil, Annular centrifugal extractor / contactor, Fast centrifugal partition chromatography
Index:
No
Number of index pages:
0
Contains images:
Yes
Number of references:
138
Number of pages:
VIII,92
File:
File access is restricted.

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