Parentage testing with STR genetic markers methodology

Postgraduate Thesis uoadl:1317533 307 Read counter

Unit:
Κατεύθυνση Κλινική Χημεία
Library of the School of Science
Deposit date:
2015-10-16
Year:
2015
Author:
Τέμο Μαρία
Supervisors info:
Μηχαήλ Κουππάρης Καθηγητής
Original Title:
Έλεγχος γονικότητας με τη μεθοδολογία STR γενετικών δεικτών
Languages:
Greek
Translated title:
Parentage testing with STR genetic markers methodology
Summary:
The aiam of this staudy was paternity/maternity testing in a total of 30
samples using STRs genetic markers method. A kit of 16 autosomal genetic
markers together with the genetic locus of amelogenin for sex determination,
was used (AmpFlSTR NGM SElect kit). In the beginning the genetic profile of
each case members was determined and the parameters CPI and W in cases of non
exclusion were calculated. The next step was the calculation of the absolute
numbers of all the alleles for genetic locus in all the samples studied.
Finally a small persentage of cases was analyzed by HLA typing. In conclusion
STR genetic markers methodology offers higher accuracy as expressed through CPI
and W statistical parameters.
Keywords:
Parentage testing, DNA profile, STRs polymorphisms, HLA antigens, Immunogenetics
Index:
Yes
Number of index pages:
viii-xii, 141-145
Contains images:
Yes
Number of references:
134
Number of pages:
xii,167
File:
File access is restricted.

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