Unit:
Τομέας ΠαθολογίαςLibrary of the School of Health Sciences
Dissertation committee:
Π. Σφηκάκης, Καθηγητής, Ιατρική, ΕΚΠΑ
Σ. Λαδάς, Ομ. Καθηγητής, Ιατρική, ΕΚΠΑ
Δ. Περρέα, Καθηγήτρια, Ιατρική, ΕΚΠΑ
Ν. Τεντολούρης, Αν. Καθηγητης, Ιατρική, ΕΚΠΑ
Κ. Μακρυλάκης, ΑΝ. Καθηγητής, Ιατρική, ΕΚΠΑ
Α. Πρωτογέρου, Αν. Καθηγητής, Ιατρική, ΕΚΠΑ
Α. Κόκκινος, Επ. Καθηγτής, Ιατρική, ΕΚΠΑ
Original Title:
Η επίδραση της κατανάλωσης τροφών με χαμηλό γλυκαιμικό δείκτη και γλυκαιμικό φορτίο στις μεταβολικές παραμέτρους σε ενήλικες με σακχαρώδη διαβήτη τύπου 2.
Summary:
Purpose
The aim of the present study was to examine the effects of consumption of desserts with low glycemic index (GI) and low glycemic load (GL), as part of a balanced hypo-caloric diet, on anthropometric and biochemical parameters in patients with type 2 diabetes mellitus (T2DM).
Methods
A total of 61 subjects with T2DM were randomly assigned to the intervention (n=30) or to the control group (n=31). Both groups followed the same hypo-caloric (-500 kcal) diet for 12 weeks. Consumption of 4 portions of low GI/GL desserts/ week was included in the diet in the intervention group while 1 portion of a usual sweet/ week was allowed to be consumed in the control group.
Results
Thirty subjects in the control and 28 subjects in the intervention group completed the trial. Body weight, body mass index and waist circumference were reduced significantly in both groups. Arterial blood pressure, fasting blood glucose, glycosylated hemoglobin, insulin and γGT were reduced significantly only in the intervention group; however, there were no significant differences between the two groups at endpoint. C-reactive protein was reduced in the intervention and HDL cholesterol was also reduced in the control group; the reductions were significantly different at the end of the trial. No significant changes were observed in the other plasma lipids, uric acid, leptin, adiponectin, and interleukin-6 in either study group.
Conclusions
Consumption of desserts with low GI/GL in a balanced hypo-caloric diet has a positive impact on anthropometric and metabolic parameters of patients with T2DM.
Main subject category:
Health Sciences
Keywords:
Low glycemic index, Glycemic load, Diabetes
Number of references:
133
File:
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