Dissertation committee:
Μελπομένη Πέππα , Αν. Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Δημήτριος Κασσάνος, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Χαράλαμπος Χρέλιας, Αν. Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Νικόλαος Παπαντωνίου, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Αναστάσιος Παπαδημητρίου, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Περικλής Παναγόπουλος, Επ. Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Γεώργιος Δημητριάδης , Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Αναστάσιος Παπαδημητρίου, Αν.Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Summary:
The purpose of the present study was to examine the impact of menstrual cycle abnormalities among patients with polycystic ovary syndrome (PCOS) on biochemical and anthropometric characteristics.We conducted a prospective observational study of patients 17-35 years of age with PCOS that attended the department of Gynecological Endocrinology of our hospital.
A total of 309 women with PCOS participated in the study.In total, 72.2% suffered from menstrual cycle disorders.In our study 15.1% of women were overweight and 24% were obese. Also, 36% of the sample had androgenetic alopecia and 56.4% had acne.
According to the stepwise discriminant analysis, we observed that glucose displayed the strongest association to the menstrual status. Significantly higher levels of LH and TSH and lower levels of prolactin were found in women with menstrual disorders compared to those with normal menstrual cycles. According to the findings of our study PCOS patients with menstrual disorders exhibit hormonal alterations and elevated fasting glucose. However, these differences remain subtle, and their impact on the future development of the metabolic syndrome cannot be fully determined.
Keywords:
Pcos,Anovulation,Menstrual Disorders,Glucose Intolerance
