Pathological and molecular approach of borderline ovarian tumors

Postgraduate Thesis uoadl:1688787 492 Read counter

Unit:
ΠΜΣ Νεοπλασματική Νόσος στον Άνθρωπο: Σύγχρονη Κλινικοπαθολογοανατομική Προσέγγιση και Έρευνα
Library of the School of Health Sciences
Deposit date:
2017-06-27
Year:
2017
Author:
Papagiannopoulou Despoina
Supervisors info:
Ελένη Καρβούνη, Αναπλ. Καθηγήτρια, Ιατρική, ΕΚΠΑ
Ολυμπία Τζάιδα, Διευθύντρια, ΕΣΥ
Ελένη Τριχιά, Διευθύντρια, ΕΣΥ
Original Title:
Παθολογοανατομική και μοριακή προσέγγιση των όγκων οριακής κακοήθειας των ωοθηκών
Languages:
Greek
Translated title:
Pathological and molecular approach of borderline ovarian tumors
Summary:
Borderline ovarian tumors consist a special scientific field for Gynecologic Oncology, as well as Surgical Pathology. Moreover a Pathologist should be extremely cautious, because a diagnosis of a borderline ovarian tumor defines the patient’s prognosis.
These tumors are classified as serous, mucinous, endometrioid, clear cell, transitional cell and mixed. According to statistical data, the majority of borderline ovarian tumors consist of serous and mucinous subtypes, whereas all the other subtypes constitute a rarity. Despite the fact that the role of immunohistochemistry is limited in identifying an ovarian tumor as of borderline malignancy, knowledge of the molecular identity of the neoplasm is important. That is because there is an increasing number of cases where the molecular identity of the tumor is included in the pathology report.
In this paper there has been an attempt to analyse the clinical, gross, microscopic, immunohistochemical and molecular features of borderline ovarian tumors, as well as new molecular data due to the consistent requirement for updating and deep knowledge of the evolution of Molecular Biology.
Main subject category:
Health Sciences
Keywords:
Borderline ovarian tumors, Ovary, Surgical pathology, Molecular approach
Index:
No
Number of index pages:
0
Contains images:
Yes
Number of references:
34
Number of pages:
68
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