Κατεύθυνση Παιδοδοντιατρική (Κλινικές Ειδικεύσεις)
Βιβλιοθήκη Οδοντιατρικής

2017-07-13

2017

Papanakou Stela

Παπαγιαννούλη Ευαγγελία, Ομότιμη Καθηγήτρια, Εργαστήριο Παιδοδοντιατρικής, Οδοντιατρική Σχολή, ΕΚΠΑ,
Κανακά-Gantenbein Χριστίνα, Καθηγήτρια, Κέντρο Νεανικού Διαβήτη , Α’ Παιδιατρική Κλινική του Πανεπιστημίου Αθηνών, νοσοκομείο «Η Αγία Σοφία», ΕΚΠΑ
Γκιζάνη Σωτηρία, Επίκουρη Καθηγήτρια, Εργαστήριο Παιδοδοντιατρικής, Οδοντιατρική Σχολή, ΕΚΠΑ

Συγκριτική μελέτη της κορτιζόλης σιέλου ηρεμίας σε σχέση με τη στοματική υγεία παιδιών και εφήβων με ρυθμισμένο και αρρύθμιστο Σακχαρώδη Διαβήτη Τύπου 1.

Greek

Comparative study of diurnal salivary cortisol and oral health status in children and adolescents with controlled and uncontrolled Diabetes Mellitus Type 1.

Type 1 Diabetes Mellitus (T1D) may serve as an unfavorable background on the development and progression of oral diseases. The aim of this study was to investigate, for the first time, the correlation between diurnal salivary cortisol levels and oral health status in T1D children and adolescents and in healthy controls. In a cross-sectional design, 53 T1D children and adolescents (age range: 8-14 years old) and 45 healthy controls (age range: 8-13 years old) were recruited from the Diabetes Centre, First Department of Pediatrics, ‘’Aghia Sophia’’ Children’s Hospital and the Paediatric Department of Dental School, of the National and Kapodistrian University of Athens (NKUA). Upon informed consent, saliva samples were obtained at awakening, 12:00, 15:00, 18:00 and 21:00 on a prescheduled Sunday using the Salivette sampling method. The area under the curve (AUC-cortisol) was calculated for cortisol profiles. Oral examination was performed by two calibrated dentists and the parameters registered were Dmfs, Plaque(PlI) and Gingival(GI) indexes. Medical and demographic information was collected using questionnaires. Multivariate regression analysis strongly associated salivary cortisol profiles with DMFs, PlI and GI indexes in both groups. A reverse mode of AUC/DMFs relation was revealed between T1D patients and healthy controls. Duration of T1D was the only disease characteristic associated to GI index. The present study provides evidence for a strong relationship between cortisol profiles and oral diseases. T1D may potentially influence oral health status due to cortisol dysregulation.

Health Sciences

Dentistry

Type 1 Diabetes Mellitus, salivary cortisol, caries, gingivitis, periodontitis, children

No

0

Yes

113

75

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https://pergamos.lib.uoa.gr/uoa/dl/object/1718339