ΠΜΣ Εργαστηριακή και Κλινική Νοσηλευτική ΚαρδιολογίαLibrary of the School of Health Sciences
Φιλιππάτος Γεράσιμος, Καθηγητής, Ιατρική, ΕΚΠΑ
Πάνου Φώτιος, Διευθυντής Ε.Σ.Υ. , Ιατρική, ΕΚΠΑ
Μπαμπάτσικου Φωτούλα, Αναπληρώτρια Καθηγήτρια, Ιατρική, ΕΚΠΑ
Ποιότητα ζωής και διαταραχές νοητικών λειτουργιών σε ασθενείς με Καρδιακή Ανεπάρκεια με χαμηλό και διατηρημένο κλάσμα εξώθησης
Quality of life and mental disorders in patients with heart failure, with low and preserved ejection fraction.
Purpose: To investigate prevalence and prognostic role of disturbed quality of life and cognitive dysfunction in patients with hospitalized HF.
Material-Method: The sample consisted of 203 patients hospitalized for heart failure, without the gender, the age, as well as their socioeconomic ideological background. The quality of life was assessed by SF-36 and the cognitive dysfunctions were assessed by Mini-Mental State Examination. The appropriate statistical process was accomplished by using the SPSS package and the x2-test, for the statistical analysis.
Results: Heart Failure patients were 71% males, of age (meanSD) 72+-12years, while they had ischemic heart failure and left ventricular ejection fraction 37+-12%. 37% from heart failure patients did not have cognitive dysfunctions, 23% had gently cognitive dysfunction and 40% had severe cognitive dysfunctions. A total of 36 patients died during a median follow-up of 315 days. The patients with severe cognitive dysfunctions leading to the increased mortality from patients without or with gently cognitive dysfunctions (log-rank p=0.006). The Mini-Mental Score was independent prognostic factor in terms of total mortality. (HR 0.95, 95% CI 0.90-0.99, p=0.027)The quality of life did not show important differences between patients with heart failure.
Conclusions: The deduction of the cognitive dysfunction is an independent prognostic factor of increased overall mortality in patients after hospitalizated for heart failure.
Main subject category:
Quality of life, Mini-Mental, Short-Form36, Heart Failure, Mental disorders
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