Quality of life and mental disorders in patients with heart failure, with low and preserved ejection fraction.

Postgraduate Thesis uoadl:2050019 443 Read counter

ΠΜΣ Εργαστηριακή και Κλινική Νοσηλευτική Καρδιολογία
Library of the School of Health Sciences
Deposit date:
Danousi Paraskevi
Supervisors info:
Φιλιππάτος Γεράσιμος, Καθηγητής, Ιατρική, ΕΚΠΑ
Πάνου Φώτιος, Διευθυντής Ε.Σ.Υ. , Ιατρική, ΕΚΠΑ
Μπαμπάτσικου Φωτούλα, Αναπληρώτρια Καθηγήτρια, Ιατρική, ΕΚΠΑ
Original Title:
Ποιότητα ζωής και διαταραχές νοητικών λειτουργιών σε ασθενείς με Καρδιακή Ανεπάρκεια με χαμηλό και διατηρημένο κλάσμα εξώθησης
Translated title:
Quality of life and mental disorders in patients with heart failure, with low and preserved ejection fraction.
Purpose: To investigate prevalence and prognostic role of disturbed quality of life and cognitive dysfunction in patients with hospitalized HF.
Material-Method: The sample consisted of 203 patients hospitalized for heart failure, without the gender, the age, as well as their socioeconomic ideological background. The quality of life was assessed by SF-36 and the cognitive dysfunctions were assessed by Mini-Mental State Examination. The appropriate statistical process was accomplished by using the SPSS package and the x2-test, for the statistical analysis.
Results: Heart Failure patients were 71% males, of age (meanSD) 72+-12years, while they had ischemic heart failure and left ventricular ejection fraction 37+-12%. 37% from heart failure patients did not have cognitive dysfunctions, 23% had gently cognitive dysfunction and 40% had severe cognitive dysfunctions. A total of 36 patients died during a median follow-up of 315 days. The patients with severe cognitive dysfunctions leading to the increased mortality from patients without or with gently cognitive dysfunctions (log-rank p=0.006). The Mini-Mental Score was independent prognostic factor in terms of total mortality. (HR 0.95, 95% CI 0.90-0.99, p=0.027)The quality of life did not show important differences between patients with heart failure.
Conclusions: The deduction of the cognitive dysfunction is an independent prognostic factor of increased overall mortality in patients after hospitalizated for heart failure.
Main subject category:
Health Sciences
Quality of life, Mini-Mental, Short-Form36, Heart Failure, Mental disorders
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