The importance of the development of upper vein syndrome in the symptomatology and clinical outcome of patients with lung cancer

Postgraduate Thesis uoadl:2748081 445 Read counter

Unit:
ΠΜΣ Καρκίνος Πνεύμονα: Σύγχρονη Κλινικοεργαστηριακή Προσέγγιση και Έρευνα
Library of the School of Health Sciences
Deposit date:
2018-04-23
Year:
2018
Author:
Micha Foteini
Supervisors info:
Παρασκευή Ρούσσου,Αναπληρώτρια Καθηγήτρια, Ιατρική, ΕΚΠΑ
Πέτρος Μπακάκος,Αναπληρωτής Καθηγητής, Ιατρική, ΕΚΠΑ
Ευάγγελος Δημακάκος, Ειδικός συνεργάτης
Original Title:
Η σημασία της ανάπτυξης συνδρόμου άνω κοίλης φλέβας στη συμπτωματολογία και στην κλινική έκβαση ασθενών με καρκίνο πνεύμονα
Languages:
Greek
Translated title:
The importance of the development of upper vein syndrome in the symptomatology and clinical outcome of patients with lung cancer
Summary:
Lung cancer is the most dominant cause of death worldwide, as it belongs to the cancer types with high mortality percentages. Histologically, it is divided into two types: the small cell lung cancer(SCLC) and the non small cell lyng cancer(NSCLC) with accounts 15% and 85% accordingly. The non small lung cancer is divided into three major pathologic subtypes:
adenocarcinoma,squamous cell carcinoma and the large cell carcinoma, which helps to define the appropriate therapy..
The present study is a retrospective analysis about the severity of developing vena cava superior syndrome and its symptoms while also the clinical outcome of the patients with lung cancer according to the demographical evidence of the patients, the existence of co-morbidity, the type and stage of the lung cancer, the haemodynamic evidence of the patients, their performance status and their therapeutic treatment.
We studied 32 patients with vena cava superior syndrome and lung cancer and we found that dyspnοea,neck and facial oedema were the most usual symptoms in patients with SVCS. 31,3% of the patients died from the disease. The mean time of survival was 15,7 months. The probability of survival of the patients in 1 year was 67,3% while the probability of survival in 2 years was 48,1%
Patients with performance status 2-4 had 7,60 greater risk of death due to disease than those patients with performance status 0-1.In addition as the level heamatocrite values the death rate of the patient with the
disease decreases. On the contrary, an increase in the values of the white blood cells increases the danger of death in the patients with the disease.
Main subject category:
Health Sciences
Keywords:
SVC syndrome, Importance of growth, Symptomatology, Clinical outcome, Lung cancer
Index:
No
Number of index pages:
0
Contains images:
No
Number of references:
328
Number of pages:
153
File:
File access is restricted only to the intranet of UoA.

Micha Foteini Master.pdf
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