Retrospective evidence for limited resection of lung cancer patients.

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Κατεύθυνση Καρκίνος Πνεύμονα: Σύγχρονη Κλινικοεργαστηριακή Προσέγγιση και Έρευνα
Library of the School of Health Sciences
Deposit date:
Apostolou Dimitrios
Supervisors info:
Παναγιώτης Σκανδαλάκης, Καθηγητής, Ιατρική σχολή, ΕΚΠΑ
Κωνσταντίνος Συρίγος, Καθηγητής, Ιατρική σχολή, ΕΚΠΑ
Kωνσταντίνος Πόταρης, Διδάκτωρ, Θωρακοχειρουργικό Τμήμα , ΓΝΝΘΑ ''Η Σωτηρία"
Original Title:
Αναδρομική καταγραφή αιτιών για περιορισμένες εκτομές ασθενών με καρκίνο πνεύμονα.
Translated title:
Retrospective evidence for limited resection of lung cancer patients.
INTRODUCTION: The role of sublobar resection (SR) in the management of early stage non-small cell lung cancer (NSCLC) has not yet been fully established. The purpose of our study was to record indications for SR, characteristics of patients and excluded tumors, as well as the outcome of patients with early stage NSCLC who underwent SR.
METHODS: We retrospectively reviewed patients underwent SR in our department during the five-year period between 2011 and 2015. We collected data on patient demographics, surgical data, and outcome of patients with early stage NSCLC who underwent SR going through a 2-year follow-up study recording recurrences and survival.
RESULTS: According to our data, 151 patients, 99 men and 52 women, underwent SR (19 segmentectomies and 132 wedge resections). Of the 151 patients, 93 had primary lung cancer, 23 metastatic tumors and 35 benign tumors. Age correlated significantly with tumor histology (p=0.002) and with hospitalization (p<0.001). Tumor localization, although more frequent in the right upper lobe, did not show statistically significant correlation with tumor histology. Regarding the utilization of SR versus lobectomy in patients with early stage NSCLC, there was no statistically significant correlation of NSCLC stage with the occurrence of recurrences in our 2-year follow up study (p=0.132), and no statistically significant benefit from the SR of tumors ≤2cm (p = 0.928) or the performance of lymph node sampling (p=0.226) with regards to recurrences.
CONCLUSION: The results of our study were consistent with other studies in the literature. Patients with early stage NSCLC who underwent SR had higher rates of local recurrences but similar morbidity, mortality and hospitalization.
Main subject category:
Health Sciences
Sublobar resection, Lung cancer
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