Κατεύθυνση Ιατρική Φυσική-Ακτινοφυσική
Library of the School of Health Sciences

2018-05-14

2018

Kriari Alexandra

Σιούντας Αναστάσιος, Αναπληρωτής Καθηγητής, τμήμα Ιατρικής, Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης
Τζιτζίκας Ιωάννης, Επίκουρος Καθηγητής, τμήμα Ιατρικής, Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης
Παπαναστασίου Εμμανουήλ, Επίκουρος Καθηγητής, τμήμα Ιατρικής, Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης

Μελέτη διορθωτικών μετακινήσεων ασθενών υπό καθοδηγούμενη από εικόνα ακτινοθεραπεία (IGRT)

Greek

Study of setup shifts of patients undergoing Image Guided Radiation Therapy (IGRT)

The purpose of this MSc Thesis is the comparison of positioning accuracy by two – dimensional kilovoltage (kV) Imaging and three – dimensional cone beam CT in patients undergoing Image Guided Radiation Therapy, IGRT. All treatments were delivered by Elekta Axesse, at University General Hospital of Thessaloniki AHEPA.
Shifts in the left – right (LR), superior – inferior (SI) and anterior – posterior (AP) dimensions were recorded using both imaging technics for 46 patients in total, with prostate, head & neck, lung and brain tumors.
The mean and the standard deviation of all set up shifts were calculated in each dimension. Moreover, systematic and random set up errors were estimated for both imaging methods. The greatest deviations occurred in patients with head & neck cancer, whereas patients with brain tumors had insignificant shifts. Patients with prostate and lung cancer resulted more considerable shifts in AP dimension. Margins resulting from setup uncertainty were estimated from the systematic and random variations.
Shifts from both imaging methods were compared by Bland – Altman analysis for each anatomic region. Even if there is a statistically considerable difference in shifts based on kV images and CBCT, in 95% confidence interval, this difference is not clinically important. However, the shifts differ enough in H&N cancer so it could be useful to examine the reasons of this difference.

Health Sciences

Cone - Beam CT, kV Imaging, IGRT, Margins, Bland altman method, Setup shifts

No

0

Yes

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https://pergamos.lib.uoa.gr/uoa/dl/object/2758654