Κατεύθυνση Σακχαρώδης Διαβήτης και Παχυσαρκία
Library of the School of Health Sciences

2018-06-20

2018

Papadokostaki Eleni

Τεντολούρης Νικόλαος, Καθηγητής, Ιατρική, ΕΚΠΑ
Μακρυλάκης Κωνσταντίνος, Αναπληρωτής Καθηγητής, Ιατρική, ΕΚΠΑ
Κόκκινος Αλέξανδρος, Αναπληρωτής Καθηγητής, Ιατρική, ΕΚΠΑ

Συσχέτιση ξηροδερμίας με δείκτες νευροπάθειας σε ασθενείς με σακχαρώδη διαβήτη

Greek

Correlation of dry skin with peripheral neuropathy in patients with diabetes mellitus

Purpose:The aim of the study is to examine the association of the degree of xerosis at the lower extremities, as assessed by clinical criteria, with the presence of peripheral neuropathy (PN) and the Neuropad test in patients with diabetes mellitus (DM).
Methods:A total of 133 patients with DM were recruited. The degree of xerosis was evaluated clinicallyaccording tothe European group on efficacy measurement of cosmetics and other topical products (EEMCO) guidance that includes total dry skin (ODS) score and the sum of signs of scaliness, roughness, redness and cracks (SRRC)score.PN was assessed with the Neuropathy Disability Score (NDS) and the Neuropathy SymptomsScore (NSS). Sudomotor dysfunction was assessed using the Neuropadtest.
Results: Both the ODSscore (p = 0.014) and theSRRC(p <0.001), weresignificantly associated with the presence of PN. However, the SRRC score wasmore statistically significantly associated with PN and in the ROC analysis appears to be a good diagnostic test for prognosis of PN (AUC = 0.695, p <0.001), withsimilar results to the Neuropad test (AUC = 0.645, p < 0.006). A SRRC score ≥2,is associated with sensitivity of 70% and specificity of 50% for the diagnosis of PN.
Conclusion: Clinical estimation of dryness of the skin at the lower extremities based on the SRRC score is a simple, practical and inexpensive method that seems to be associated with PN and could therefore, be included in the clinical foot examination in patients with DM.

Health Sciences

Xerosis, Dry skin, Diabetes mellitus, Peripheral neuropathy, Neuropad test

No

0

Yes

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https://pergamos.lib.uoa.gr/uoa/dl/object/2775139