Relationship between sleep duration and morbidity and mortality from cardiovascular disease: a systematic review and meta-analysis

Postgraduate Thesis uoadl:2775159 422 Read counter

Unit:
Postgraduate Programme Biostatistics & Health Science Data
Library of the School of Health Sciences
Deposit date:
2018-06-20
Year:
2018
Author:
Fountas Epameinondas
Supervisors info:
Κατσουγιάννη Κλέα , Καθηγήτρια , Ιατρική Σχολή , ΕΚΠΑ
Μπουρνέτας Απόστολος ,Καθηγητής , Τμήμα Μαθηματικών , ΕΚΠΑ
Τουλιάτου Αικατερίνη , Διδάκτωρ ΕΚΠΑ - διευθύντρια ΕΣΥ , Γ.Ν.Αθηνών "Γ.Γεννηματάς"
Original Title:
Συσχέτιση της διάρκειας του καθημερινού ύπνου με την επίπτωση και τη θνησιμότητα από καρδιαγγειακά νοσήματα: Συστηματική ανασκόπηση και μετα-ανάλυση
Languages:
Greek
Translated title:
Relationship between sleep duration and morbidity and mortality from cardiovascular disease: a systematic review and meta-analysis
Summary:
Aim
To investigate possible relationship between duration of daily sleep and morbidity or mortality from cardiovascular disease.
Methods
Systematic research through electronic databases was performed to find prospective studies that were published within last 5 years with population of interest adults without known cardiovascular disease. The exposure was duration of daily sleep and the outcome was morbidity and mortality from stroke, coronary heart disease or cardiovascular disease as a whole.
Results
11 publications were included in this meta-analysis. Two groups,one with short (<6h) and another with long (>9h) daily sleep duration were compared to the reference group (6-9h). For the first comparison ,10 out of 11 studies were included and for the second one, 7 out of 11. Both short (RR=1.11 , 95%CI 1.03-1.19 , P=0.007) and long (RR=1.32 , 95%CI 1.22-1.43 , P<0.001) sleep duration were associated with increased risk of cardiovascular disease or cardiovascular death. Neither publication bias, nor significant heterogeneity was observed. Medium scale heterogeneity was found in analysis of short sleep duration (Q=17.05 , p=0.048 , I2=47.2%), but after complementary analysis it proved to be non-influencial to final results.
Conclusion
Any deflection from normal daily sleep duration is statistically related to increased risk of cardiovascular disease and cardiovascular death.
Main subject category:
Health Sciences
Keywords:
Sleep, Sleep duration, Cardiovascular disease, Morbidity, Mortality, Meta-analysis, Systematic review
Index:
No
Number of index pages:
0
Contains images:
Yes
Number of references:
89
Number of pages:
85
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