Unit:
ΠΜΣ Σακχαρώδης Διαβήτης και ΠαχυσαρκίαLibrary of the School of Health Sciences
Supervisors info:
Νικόλαος Τεντολούρης, Αναπλ. Καθηγητής, Ιατρική, ΕΚΠΑ
Μακρυλάκης Κωνσταντίνος, Αναπλ. Καθηγητής, Ιατρική, ΕΚΠΑ
Κόκκινος Αλέξανδρος, Αναπλ. Καθηγητής, Ιατρική, ΕΚΠΑ
Original Title:
Σακχαρώδης διαβήτης και μυελοδυσπλαστικό σύνδρομο
Translated title:
Diabetes mellitus and myelodysplastic syndrome
Summary:
Diabetes Mellitus (DM) and Myelodysplastic syndromes (MDS) as they are two diseases of high prevalence in the population, their coexistence is expected to be higher in the future. When these conditions co-exist, DM may influence the survival of the patients either directly or via organ damage. The data from our study and from others although limited did not show any effect on the survival of patients with MDS and DM. It is possible of course to limit the applicability of intensive therapeutic interventions in MDS. Patients with DM associated with severe organ damage are not ideal candidates for aggressive treatment in MDS. On the other hand it seems that in patients with high risk MDS, with low life expectancy, aggressive control of DM did not show any advantage while in low risk MDS and high life expectancy, good control of DM, may show positive results.
The current and the future knowledge concerning the pathogenetic mechanisms, the clinical and epidemiological data for the coexistence of the two diseases could be used to improve the prognosis and outcome for these patients.
Main subject category:
Health Sciences
Keywords:
Diabetes mellitus, Myelodysplastic syndrome
