Atherosclerotic disease of the subclavian artery: comparison between endovascular and open treatment

Postgraduate Thesis uoadl:2775246 321 Read counter

Unit:
Διακρατικό ΠΜΣ Ενδαγγειακές Τεχνικές
Library of the School of Health Sciences
Deposit date:
2018-06-21
Year:
2018
Author:
Galyfos Georgios
Supervisors info:
Γερουλάκος Γεώργιος, Καθηγητής, Ιατρική, ΕΚΠΑ
Χατζηιωάννου Αχιλλέας, Καθηγητής, Ιατρική, ΕΚΠΑ
Κακίσης Ιωάννης, Αναπληρωτής Καθηγητής, Ιατρική, ΕΚΠΑ
Original Title:
Αθηροσκληρωτική νόσος της υποκλειδίου αρτηρίας: σύγκριση ενδαγγειακής και ανοικτής αντιμετώπισης
Languages:
Greek
Translated title:
Atherosclerotic disease of the subclavian artery: comparison between endovascular and open treatment
Summary:
Aim of the study: Aim of this study was to compare open and endovascular treatment in patients with atherosclerotic lesions of the subclavian artery, as far as early and late outcomes are concerned.
Materials and Methods: This was a systematic review, where the following search engines were utilized: Pubmed, Embase, Scopus and Cochrane Library (from November to December 2017). Eligible studies compared early and late major outcomes between open and endovascular therapy in patients suffering from atherosclerotic disease of the subclavian artery.
Results: Overall, 7 clinical studies included 731 patients undergoing 760 procedures in total (297 endovascular and 463 open procedures). The majority of procedures (99.7%) referred to symptomatic patients, and more patients undergoing open surgery had an occlusion compared to patients undergoing angioplasty where the majority had a stenosis. Regarding early outcomes (30-day death, cardiac events, technical success, central nerve system events), there was no difference between the two methods. Only peripheral nerve system complications were more prevalent in patients undergoing open repair. Regarding late outcomes, open repair was associated with significantly higher 1-, 3- and 5-year primary patency rates, compared to endovascular therapy. However, 5-year freedom from recurrent symptoms as well as 5-year overall survival showed no difference.
Conclusions: Open and endovascular repair in patients with atherosclerotic lesions of the subclavian artery do not show any difference concerning most of early major outcomes. However, open surgery seems to prevail regarding long-term primary patency, although long-term survival and freedom from recurrent symptoms show no difference.
Main subject category:
Health Sciences
Keywords:
Subclavian artery, Endovascular treatment, Open treatment, Angioplasty
Index:
No
Number of index pages:
0
Contains images:
Yes
Number of references:
86
Number of pages:
84
File:
File access is restricted only to the intranet of UoA.

Galyfos Georgios Master.pdf
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