Supervisors info:
Κυρίτση Ελένη, Καθηγήτρια, Νοσηλευτική, Πανεπιστήμιο Δυτικής Αττικής
Βλάχου Ευγενία, Αναπληρώτρια Καθηγήτρια, Νοσηλευτική, Πανεπιστήμιο Δυτικής Αττικής
Κουτελέκος Ιωάννης, Καθηγητής, Νοσηλευτική, Πανεπιστήμιο Δυτικής Αττικής
Summary:
Introduction: Growth failure is a major complication of chronic kidney disease and the pathogenesis is not fully clarified. Usually it is multifactorial. Initial renal disease, age of onset of chronic kidney disease, reduced calories and protein intake, acidosis, water and electrolyte disturbances, renal osteodystrophy, anemia, and hormonal disturbances adversely affects the somatic growth.
Purpose of the study: The purpose of this research is to investigate the height and weight increase of children with chronic kidney disease stage 3,4 and 5.
Material and Methods: We studied 50 children with chronic kidney disease stage 3, 4, and 5 admitted in P&A Children’s hospital. The data excluded from the charts of patients. Statistical analysis became with t-test, anova and pair t-test. Statistical significant is <0.05%.
Results: The sample of our study was 50 children with stage 3,4 ,5 (70% males, 50% stage 5). Among 50 children 50% were predialysis, 26% received hemodialysis, 8% peritoneal dialysis, 16% both hemodialysis and peritoneal dialysis. In absolute number of centimeters in height growth among the measurements from the first to the tenth measurement, there was a statistically significant differences of deterioration, p<0,001, except of the measurement between the ninth and the tenth, p=0,003.
At the beginning of the study 38% and 42% were below 3rd percentile for the height and weight respectively. Regarding weight, there is significant deterioration between first recording and after 1 year of follow up (second recording)p=0.049. Additionally, between recordings, there was significant increase in absolute values (p>0.001) except recording 9th and 10th. p=0.043.
Conclusions: Growth of children with chronic kidney disease is significantly inferior at the time of diagnosis and it remains adversely affected at all stages of the disease. It is likely to be improved with the appropriate treatment of risk factors such as anemia, acidosis, growth hormone deficiency.
Keywords:
Chronic kidney disease, Children, Growth, Hemodialysis