Health‐related quality of life after stereotactic vacuum – assisted breast biopsy utilizing the Breast Lesion Excision System (B.L.E.S.) - Short-term and long-term effects

Doctoral Dissertation uoadl:2778938 172 Read counter

Τομέας Χειρουργικής
Library of the School of Health Sciences
Deposit date:
Matiatou Maria
Dissertation committee:
Γεώργιος Κ. Ζωγράφος, Καθηγητής, Ιατρική, ΕΚΠΑ
Μανούσος Κωνσταντουλάκης, Καθηγητής, Ιατρική, ΕΚΠΑ
Ευάγγελος Μενενάκος, Αναπληρωτής Καθηγητής, Ιατρική, ΕΚΠΑ
Νικόλαος Αλεξάκης, Αναπληρωτής Καθηγητής, Ιατρική, ΕΚΠΑ
Δημήτριος Θεοδώρου, Αναπληρωτής Καθηγητής, Ιατρική, ΕΚΠΑ
Γεώργιος Θεοδωρόπουλος, Αναπληρωτής Καθηγητής, Ιατρική, ΕΚΠΑ
Κωνσταντίνος Γ. Τούτουζας, Αναπληρωτής Καθηγητής, Ιατρική, ΕΚΠΑ
Original Title:
Ποιότητα ζωής μετά από εφαρμογή της ελάχιστα επεμβατικής βιοψίας του μαστού με τη μέθοδο B.L.E.S. (Breast Lesion Excision System) - Βραχυπρόθεσμες και μακροπρόθεσμες επιπτώσεις
Translated title:
Health‐related quality of life after stereotactic vacuum – assisted breast biopsy utilizing the Breast Lesion Excision System (B.L.E.S.) - Short-term and long-term effects
Background-Aim: B.L.E.S. (Breast Lesion Excision System) is a well-established minimally invasive stereotactic vacuum assisted biopsy method utilizing radiofrequency to evaluate non-palpable breast lesions. The aim of this study is to evaluate short and long-term effects of B.L.E.S. biopsy procedure on health-related quality of life (HRQoL) and to identify factors that could possibly modify these effects.
Methods: This study included 207 women who underwent B.L.E.S. biopsy and were diagnosed with a benign breast lesion. Health related quality of life was assessed by EQ-5D (EuroQol Group) and SF-36v2 (QualityMetric Incorporated) questionnaires at three time points: a) before biopsy (baseline measurement), b) 4 days after biopsy (short-term measurement), c) 6 months after biopsy (long-term measurement). Furthermore, socioeconomic, medical and seasonal parameters were studied, for the evaluation of their effect on health-related quality of life after the B.L.E.S. biopsy procedure.
Results: At the baseline measurement, women present psychological distress that seems to ameliorate as shown by subsequent measurements. At the short-term measurement, women present deterioration of physical health, influencing seriously their activities, mostly due to the feeling of pain. At the long-term measurement, the physical health scores remain in low levels, although higher when compared to the short-term measurement, while the feeling of pain is absent. Marital status and seasoning are factors affecting short-term scores of HRQoL while age, menopausal status and body mass index (BMI) are factors affecting long-term scores of HRQoL.
Conclusions: B.L.E.S biopsy exerts a negative effect on health-related quality of life prior to its performance on the psychological level and after its performance on the physical - functioning level, while the factor of pain should be considered to play an important role in the short-term.
Main subject category:
Health Sciences
Quality of life ( QOL), Health related quality of life, Minimal invasive technique, Radiofrequency, Non palpable mammographic lesions, Calcification, Microcalcifications, Long-term effect, short-term effect, Stereotactic breast biopsy
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