Electromyographic findings after epidural steroid injections in patients with low back pain

Doctoral Dissertation uoadl:2800084 230 Read counter

Library of the School of Health Sciences
Faculty of Medicine
Τομέας Χειρουργικής
Deposit date:
Angelopoulou Athina
Dissertation committee:
Γεωργία Γερολουκά-Κωστοπαναγιώτου, Καθηγήτρια, Ιατρική, ΕΚΠΑ
Παρασκευή Ματσώτα, Αναπληρώτρια Καθηγήτρια, Ιατρική, ΕΚΠΑ
Κασσιανή Θεοδωράκη, Αναπληρώτρια Καθηγήτρια, Ιατρική, ΕΚΠΑ
Χρυσούλα Στάϊκου, Επίκουρη Καθηγήτρια, Ιατρική, ΕΚΠΑ
Χρυσάνθη Μπατιστάκη, Επίκουρη Καθηγήτρια, Ιατρική, ΕΚΠΑ
Θεοδόσιος Σαραντέας, Επίκουρος Καθηγητής, Ιατρική, ΕΚΠΑ
Τατιάνη Σιδηροπούλου, Επίκουρη Καθηγήτρια, Ιατρική, ΕΚΠΑ
Original Title:
Ηλεκτρομυογραφικά ευρήματα πριν και μετά την επισκληρίδιο έγχυση κορτικοστεροειδών φαρμάκων για την αντιμετώπιση του πόνου σε ασθενείς με οσφυαλγία
Translated title:
Electromyographic findings after epidural steroid injections in patients with low back pain
Epidural steroid injections (ESIs) are commonly used in the management of chronic low back and leg pain. The aim of this study was to investigate the short and long-term electromyographic and clinical outcome of patients with chronic radicular pain after ESIs. This prospective, open-label study, included patients with chronic radicular pain due to disc herniation or spinal stenosis, who underwent interlaminar, fluoroscopy-guided ESIs. Patients were assessed before ESIs, as well as after 6 and 12 months, clinically (VAS 0-10, BPI, DN4, Rolland Morris, DASS, STAI) and electromyographically, as for the improvement of spontaneous activity (SA), and of motor unit recruitment/interference pattern (IP/MUR).xxThirty nine patients were studied, 20(51.3%). A significant improvement in VAS, RM, DN4 and BPI was revealed, mainly during the first 6 months (p<0.05). Statistically significant improvement was revealed in MUR/SA for almost all nerve roots studied. Patients with disc herniation showed a greater improvement in mean difference of MUR/SA (p<0.05) (with a prognostic value of radicular LBP versus spinal stenosis in short [VAS p=0.042] and long-term improvement of pain [VAS p=0.009]. The independent variables “MUR” and “SA” had a significant prognostic value for improvement of pain (VAS: R2=0.287, p=0.032 and VAS: R2=0.277, p=0.036 respectively).Electromyographic and clinical findings indicated benefit from epidural steroid injections. Patients with disc herniation exhibited a better outcome, especially during the first 6 months post-treatment.Keywords: low back pain; chronic; electromyography; epidural; steroids Running title: Electromyography and epidural steroid injections Funding: None
Main subject category:
Health Sciences
Angelopoulou, EMG, Epidural, Analgesia, Radiculopathy
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AGGELOPOULOU_PhD_final September 28 2018.pdf
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