Κατεύθυνση Προστασία και Πρόληψη των κινδύνων στην Εργασία και το Περιβάλλον
Library of the School of Health Sciences

2018-10-18

2018

Polychronakou Panagiota

Ε. Ριζά, ΕΕΔΙΠ, Ιατρική, ΕΚΠΑ
Θ. Ψαλτοπούλου, Αναπλ. Καθηγήτρια, Ιατρική, ΕΚΠΑ
Μ. Καντζάνου, Επικ. Καθηγήτρια, Ιατρική, ΕΚΠΑ

Χλωριωμένοι αλειφατικοί υδρογονάνθρακες (παραγωγή και χρήση) - επαγγελματική έκθεση και καρκινογένεση, σύγχρονες επιστημονικές και ευρωπαϊκές νομοθετικές εξελίξεις

Greek

Chorinated aliphatic hydrocarbons (production and uses)-occupational expose and carcinogenesis, contemporary scientific developments and the new European legislation

In the European Union, cancer is the first cause of death associated with work. In its reports, the European Commission reports that in 2012, 91500-150500 people were first diagnosed with cancer with previous exposure to carcinogens at work, and 57700-106500 cancer deaths were attributable to exposure to work-related carcinogens. It is estimated that 32 million workers are exposed to carcinogens, while work-related cancer kills 10 people per hour.
This paper examines the health risks and especially the carcinogenicity of a group of chemical agents, chlorinated aliphatic hydrocarbons. For the vinyl chloride monomer belonging to this group and proven carcinogen, it took several years for the causal relationship to be confirmed with sufficient evidence between exposure to and the induction of cancer in humans. Initially, cancer was observed in experimental animals after exposure and then also confirmed for workers from epidemiological studies.
The World Organization for Cancer Research (IARC) in its recent editions in 2014 and 2017 has focused on some chlorinated aliphatic hydrocarbons mentioned in this paper. The IARC carcinogen classification is taken into account by the European Commission in drafting and the new European legislation and then voting in by the European Parliament. Many of the chemical agents reviewed in the newly registered data by the European Chemicals Agency (ECHA) are classified as substances of very high concern (SVHC) for their carcinogenicity in accordance with the EU REACH Regulation. The European Commission has already started the procedure for amending the CMD Directive and introducing limit values for exposure to carcinogens, recognizing that the setting of minimum exposure limits is economically and socially beneficial in preventing the proliferation of the disease.
The path from the exposure to the emergence of a disease such as cancer could be prevented by preemptive measures for occupational health. It is necessary to revise the existing legal framework for the health and safety while taking into account the existing situation in society due to the introduction of stricter national legislation and to strengthen the National Health System to ensure the health of workers and the public health

Health Sciences

Chorinated aliphatic hydrocarbons, Occupational health, Occupational exposure, Carcinogen, Cancer, REACH Regulation, CLP Regulation, CMD Directive, CAD Directive, National legislation, European legislation

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https://pergamos.lib.uoa.gr/uoa/dl/object/2811783