Acute kidney injury (AKI) involve severely ill patients treated in Intensive Care Units (ICU)-systematic review

Postgraduate Thesis uoadl:2820409 316 Read counter

Unit:
Κατεύθυνση Μονάδες Εντατικής Θεραπείας και Επείγουσα Νοσηλευτική
Library of the School of Health Sciences
Deposit date:
2018-12-12
Year:
2018
Author:
Bompotas Marinos-Stavros
Supervisors info:
Χριστίνα Μαρβάκη, Ομότιμη Καθηγήτρια, Νοσηλευτική, Πανεπιστήμιο Δυτικής Αττικής
Γεωργία Τουλιά, Επίκουρη Καθηγήτρια, Νοσηλευτική, Πανεπιστήμιο Δυτικής Αττικής
Παρασκευή Κατσαούνου, Επίκουρη Καθηγήτρια, Ιατρική, ΕΚΠΑ
Original Title:
Προγνωστικοί δείκτες οξείας νεφρικής βλάβης σε βαρέως πάσχοντες ασθενείς-συστηματική ανασκόπηση
Languages:
Greek
Translated title:
Acute kidney injury (AKI) involve severely ill patients treated in Intensive Care Units (ICU)-systematic review
Summary:
Introduction: Most cases of acute kidney injury (AKI) involve severely ill patients treated in Intensive Care Units (ICU) by 25-30%. Diagnosis of acute kidney injury (AKI) is performed by a non-sensitive marker of serum creatinine, resulting in its inadequate treatment and increased mortality. New indicators of acute kidney injury (AKI) with predictive value are needed.
Aim: The aim of the study was to investigate prognostic indicators of acute kidney injury (AKI) in severely ill patients.
Methodology: This study is a systematic review based on the search for bibliography, published research, systematic reviews and metanalysis in international (Pubmed, Cinahl, Medline) and Greek (Iatrotek) electronic data bases on prognostic indicators of acute kidney injury (AKI) in severely ill patients with a duration from 2010 to 2018.
Results: The most prominent prognostic indicators of acute kidney injury (AKI) in the severely ill patients emerging from the current systemic review are neutrophil gelatinase-associated lipocalin (NGAL), cystatin C, interleukin 18 (IL 18) and kidney injury molecule 1 (KIM-1). Their high levels of serum and urine were associated with the prognosis of acute kidney injury (AKI) in severely ill patients.
Conclusions: The prognostic indicators emerged from this study need to be included in clinical practice as they contribute to the timely treatment of acute kidney injury (AKI) and to reducing the mortality of severely ill patients. The most predominant prognostic indicators were neutrophil gelatinase-associated lipocalin (NGAL) and cystatin C. All editors are recommended to further investigate their credibility and prognostic ability.
Key words: acute kidney injury (AKI), neutrophil gelatinase-associated lipocalin (NGAL), cystatin C, interleukin 18(IL-18), kidney injury molecule 1 (KIM-1).
Main subject category:
Health Sciences
Keywords:
Acute kidney injury (AKI), Neutrophil gelatinase-associated lipocalin (NGAL), Cystatin C, Interleukin 18(IL-18), Kidney injury molecule 1 (KIM-1).
Index:
No
Number of index pages:
0
Contains images:
Yes
Number of references:
60
Number of pages:
58
File:
File access is restricted only to the intranet of UoA.

ΔΙΠΛΩΜΑΤΙΚΗ ΜΑΡΙΝΟΣ ΜΠΟΜΠΟΤΑΣ.2018 (1).pdf
1 MB
File access is restricted only to the intranet of UoA.

 


ΔΙΠΛΩΜΑΤΙΚΗ ΜΑΡΙΝΟΣ ΜΠΟΜΠΟΤΑΣ.2018 (1).zip
159 KB
File access is restricted only to the intranet of UoA.