ΠΜΣ Παθολογία της ΚύησηςLibrary of the School of Health Sciences
Παπαντωνίου Νικόλαος, Ομότιμος Καθηγητής, Ιατρική, ΕΚΠΑ
Κασσάνος Δημήτριος, Ομότιμος Καθηγητής, Ιατρική, ΕΚΠΑ
Χρέλιας Χαράλαμπος, Αναπληρωτής Καθηγητής, Ιατρική, ΕΚΠΑ
Μελέτη των επιπτώσεων σακχαρώδους διαβήτη τύπου Ι στην κύηση, τον τοκετό και τη λοχεία.
Study of the effects of type 1 diabetes mellitus on pregnancy and childbirth
Introduction: The purpose of this review is to examine the effects of diabetes mellitus
during pregnancy, labor and postnatal.
Methods: It is a literature review. Pubmed and Cochrane database were used to find out
surveys about the effects of diabetes mellitus during pregnancy, labor and postnatal.
Results: Diabetes mellitus (DM) is characterized by hyperglycemia. During pregnancy,
there is a progressive decrease in insulin action and maintenance of homeostasis occurs
through a compensatory increase in insulin secretion. There is a reduced insulin secretion
(deficiency) or decreased activity of normal or even elevated insulin levels resulting in
The DM is associated with both microvascular and macrovascular disease. The
severity of the DM is assessed by White rank. Alternatively, women are divided into two
categories, depending on whether or not there is a vascular disease. On angiopathy, the
risk of placental dysfunction and damage to the mother's target organs is greater. The
objectives of dietary management include the achievement of euglycemia, ketosis
prevention, normal weight gain and ensuring the "good status" of the fetus.
Conclusions: Today, the reduction in perinatal mortality is mainly due to better control
of diabetes (as well as out-of-pregnancy) from the combined effort of a group of doctors
that includes an endocrinologist and requires the active involvement of the patient, to
which all the dangers. In addition to routine tests, pregnant women with DM I should be
advised to measure HbA1c, TSH, fT3, fT4, urea, creatinine and 24 hour urine albumen
on the first visit. In addition, electrocardiography and eye catheterisation should be
Unlike in the past, in pregnant women with DM 1 and a smooth course of
pregnancy, a normal birth can be made by completing the 40 weeks of pregnancy.
Breastfeeding in these women should be encouraged. Insulin requirements and daily
caloric intake should be re-evaluated at the time.
Main subject category:
Diabetes mellitus, Insulin, High risk pregnancy
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