Unit:
Κατεύθυνση Μεταβολικά Νοσήματα των ΟστώνLibrary of the School of Health Sciences
Author:
Hadjimichael Argyris
Supervisors info:
Λυρίτης Γεώργιος, Ομότιμος Καθηγητής, Ιατρική, ΕΚΠΑ
Δοντά Ισμήνη, Καθηγήτρια, Ιατρική, ΕΚΠΑ
Τριανταφυλλόπουλος Ιωάννης, Επίκουρος Καθηγητής, Ιατρική, ΕΚΠΑ
Original Title:
Παράγοντες κινδύνου για λοιμώξεις επί ολικών αρθροπλαστικών ισχίου και γόνατος
Translated title:
Risk factors for the development of periprosthetic infection, in patients treated with hip or knee arthroplasty
Summary:
Osteoarthrosis is a common degenerative and progressive disease, involving the articular cartilage as well as the subchondral bone and the soft tissues of the hip and knee joints. The incidence of hip and knee osteoarthrosis has increased over the last twenty years and is expected to increase even further. Approximately, 40% of men and 47% of women over 65 years old suffer from symptomatic osteoarthrosis that eventually requires surgical treatment by an orthopedic surgeon. In 2010 around 2.5 million patients were operated for total hip replacement and around 4.7 people with knee osteoarthrosis had a total knee replacement in the United States of America.
Acute periprosthetic joint infection, with Staphylococcus aureus being the most common and aggressive pathogen is a very threatening complication for the whole health status of the patient. The need for revision procedures due to periprosthetic hip infection is expected to be doubled in 2026 and is already doubled due to periprosthetic knee infection in 2015.
The risk factors for hip and knee periprosthetic joint infections appear in the preoperative period, as well as intraoperatively and continue to be harmful both in the postoperative period and after the patient’s discharge from the hospital. Some risk factors accompany the patient before the operation (e.g. diabetes mellitus, rheumatoid arthritis, and smoking) and others appear under specific circumstances in which the surgical procedure is performed (e.g. type of prosthesis, type of anesthesia, duration of the procedure). Postoperative risk factors (e.g. cardiovascular complications, use of non-steroid anti-inflammatory drugs, dental procedures) can also lead to periprosthetic joint infections even in long period after primary surgery and must been recognized and treated directly and effectively.
The aim of this article is to present extensively the variety of risk factors, associated with periprosthetic hip and knee infections. Many risk factors can be controlled with the use of specific preventive and therapeutic interventions by orthopedic surgeons.
Main subject category:
Health Sciences
Keywords:
Osteoarthrosis, Total hip replacement, Total knee replacement, Periprosthetic infections, Risk factors
Number of references:
157
