Unit:
Τομέας ΠαθολογίαςLibrary of the School of Health Sciences
Dissertation committee:
Ρηγόπουλος Δημήτριος, Καθηγητής, Ιατρική, ΕΚΠΑ
Αργυρώ Χατζηϊωάννου, Αναπληρώτρια Καθηγήτρια, Ιατρική, ΕΚΠΑ
Αλέξανδρος Στρατηγός, Καθηγητής, Ιατρική, ΕΚΠΑ
Παναγιώτης Σταυρόπουλος, Καθηγητής, Ιατρική, ΕΚΠΑ
Ηλέκτρα Νικολαΐδου, Αναπληρώτρια Καθηγήτρια, Ιατρική, ΕΚΠΑ
Ευαγγελία Παπαδαυίδ, Αναπληρώτρια Καθηγήτρια, Ιατρική, ΕΚΠΑ
Κωνσταντίνος Βλάσσης, Αναπληρωτής Καθηγητής, Ιατρική, ΕΚΠΑ
Original Title:
Αναδρομική και επιδημιολογική μελέτη της ευαισθητοποίησης ασθενών πασχόντων από δερματίτιδα μετά από επιδερμικές δοκιμασίες με εξ' επαφής αλλεργιογόνα στον ελλαδικό χώρο
Translated title:
Retrospective and epidemiological studu of allergen sensitization in contact dermatitis in Greece
Summary:
Background: Contact dermatitis is a common skin disorder related to
environmental exposures affecting, all age groups, and both genders. The pattern
of contact sensitization to a series of allergens included in the European baseline
series has already been studied for a number of EU countries by the ESSCA
Network. The current study aims to explore the patterns of contact dermatitis in
Greece through a patch test against a large number of allergens provoking contact
dermatitis. Methods: Retrospective analysis of routine data of 1978 patients were
collected during 2014-2016 in the Laboratory of Patch Testing, National Referral
Centre of Occupational Dermatoses. Sensitization in all cases was tested with a
battery of 28 allergens of the European baseline series and additional ones
aiming to identify new sensitizations to inform the national baseline of allergens;
information for an extended MOAHLFA index was also collected. Results: One
at least positive result was found in 61.5% of the patients while 19.1% of those
found to be sensitized in two or more allergens. Nickel Sulphate, Fragrance Mix
and Balsam of Peru were the most prevalent allergens in the total population, as
well as with respect to gender. Nickel is the most frequent allergen of baseline
series, a result which is in agreement with other reports. Conclusion: Our results
are consistent with previous studies across Europe. Among contact dermatitis
studies, there is a sufficient, country-dependent degree of variation. One possible
reason for this differentiation is that it may due to the differences patch test
measurement methodology, the selection of patient cohort and finally the actual
differences that exist due to different social or national characteristics. Finally,
this study highlights the significance of the phenomenon of allergic contact
dermatitis and shows that its systematic observation along with Greece’s
international in international registries is imperative.
Main subject category:
Health Sciences
Keywords:
Contact dermatitis, Sensitization, Allergen, Prevalence, Greece
Number of references:
173
