The investigation of morbidity and mortality among people who injects drugs with HBV/HCV infection with and without HIV co-infection comparatively to vulnerable groups of general population sufferers: Immigrants and homosexual sufferers

Postgraduate Thesis uoadl:2837585 91 Read counter

Unit:
Κατεύθυνση Οργάνωση και Διοίκηση Υπηρεσιών Υγείας
Library of the School of Health Sciences
Deposit date:
2018-12-13
Year:
2018
Author:
Babagiannou Rosanna
Supervisors info:
Μαριάννα Διομήδους, Αναπλ. Καθηγήτρια, Νοσηλευτική, ΕΚΠΑ
Ιωαννης Μαντάς, Καθηγητής, Νοσηλευτική, ΕΚΠΑ
Νικόλαος Φώτος, Επικ. Καθηγητής, Νοσηλευτική, ΕΚΠΑ
Original Title:
Η διερεύνηση της νοσηρότητας και της θνητότητας στους ΧΕΝ με λοίμωξη HBV/HCV με και χωρίς συλλοίμωξη HIV συγκριτικά με τις ευπαθείς ομάδες πασχόντων του γενικού πληθυσμού: Mεταναστών και ομοφυλόφιλων πασχόντων
Languages:
English
Translated title:
The investigation of morbidity and mortality among people who injects drugs with HBV/HCV infection with and without HIV co-infection comparatively to vulnerable groups of general population sufferers: Immigrants and homosexual sufferers
Summary:
Hepatitis B and C infection remains a major public health problem. Intermediate endemic regions include Mediterranean and Asian countries (HBV 20-60%, HBsAg 2-7% and anti-HCV 1-2%), while the highest endemic rate was found in Africa, South-East Asia and Latin America (HBV markers > 60%, HBsAg 8-15% and anti-HCV > 2%). Greece belongs to countries with intermediate endemicity, with wide variation in seropositivity in different regions and populations, with increased frequency of transmission in intravenous drug users, homosexual men and migrants.
The purpose of this study is to investigate the morbidity and mortality of patients infected with HBV / HCV virus with and without HIV co-infection and compare to homosexual and migrant infected with HBV / HCV population in order to examine the prevailing situation in Greece.
The followed method was the quantification analysis of morbidity and mortality of intravenous drug users, migrants and homosexuals infected with hepatitis B or C virus, seropositive and seronegative to HIV by stratified sampling. For the statistical analysis and processing of data, the statistical package for Social Sciences (SPSS) version 25 was used.
The results of the study, conclude that hepatitis B and C infection is not related to gender but there is a statistically significant age and morbidity correlation of HBV / HCV virus, as there is a positive correlation between age and mortality. The incidence of hepatocellular carcinoma is correlated with the use of intravenous drugs and Hepatitis C, but there is no positive correlation with HIV co-infection. There is also a statistically significant correlation of Hepatitis C among IDUs with HIV co-infection, and statistically less significant correlation among homosexual men, the mean prevalence of Hepatitis B and C was found to be higher for migrants from non-EU intravenous drugs users.
Main subject category:
Health Sciences
Keywords:
Hepatitis B, Hepatitis C, HIV co-infection, Hepatocellular carcinoma, IDU, Homosexuals, Migrants
Index:
No
Number of index pages:
0
Contains images:
Yes
Number of references:
193
Number of pages:
150
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