Unit:
Κατεύθυνση Κλινική Νοσηλευτική: Παιδιατρική ΝοσηλευτικήLibrary of the School of Health Sciences
Author:
Zampoukas Christodoulos
Supervisors info:
Μάτζιου-Μεγαπάνου Βασιλική, Καθηγήτρια, Νοσηλευτική, ΕΚΠΑ
Τσουμάκας Κωνσταντίνος, Καθηγητής, Νοσηλευτική, ΕΚΠΑ
Παυλοπούλου Ιωάννα, Αναπληρώτρια καθηγήτρια, Νοσηλευτική, ΕΚΠΑ
Original Title:
Η αποτελεσματικότητα της χρήσης υπέρτονου διαλύματος 3% και NaCl 0,9% στην αναπνευστική λειτουργία βρεφών με βρογχιολίτιδα
Translated title:
The efficacy of nebulized hypertonic saline 3% and normal saline 0,9% in respiratory function of infants with bronchiolitis
Summary:
Introduction: Acute bronchiolitis is the most common manifestation of lower respiratory tract infection in infancy. Both pharmaceutical and non-pharmaceutical treatment of acute bronchiolitis have an impressive variety. Part of this treatment is also the use of nebulized hypertonic saline 3% to shorten the duration of hospitalization and improve respiratory function.
Objectives: The purpose of this systematic review was to evaluate the effectiveness of using the hypertonic saline 3% and normal saline to the respiratory function of infants with bronchiolitis.
Material and Methods: An electronic search was carried out in the Pubmed, Cochrane, Science Direct and Jama Netwrok databases from 2010 until 31 September 2018. All the articles resulting from the search for the international literature were 185 and 14 met the selection criteria and were included in the study.
Results: This systematic review focused on the comparison of the 3% hypertonic solution with 0.9% sodium chloride solution and the effects that may be present on the respiratory function of infants with bronchiolitis. In particular, the effects of administration were the length of stay, improvement in respiratory function using assessment tools, admission rates and the appearance of side effects from the hypertonic solution 3%. Of the 14 studies, 4 studies showed positive results from the administration of the 3% solution to the parameters tested and the other 10 showed no difference between the 2 solution regimens.
Conclusions: The use of the nebulised 3% hypertonic solution does not appear to be superior to 0.9% sodium chloride in improving the respiratory function of infants with bronchiolitis as well as during hospitalization and the rate of hospital admission.
Main subject category:
Health Sciences
Keywords:
Nebulized hypertonic saline 3%, Bronchiolitis, Normal saline, Hypertonic saline, respiratory function
