Gestational diabetes

Postgraduate Thesis uoadl:2838402 471 Read counter

Unit:
Κατεύθυνση Παθολογία της Κύησης
Library of the School of Health Sciences
Deposit date:
2018-12-21
Year:
2018
Author:
Matthaiolampaki Foteini
Supervisors info:
Νικόλαος Παπαντωνίου, Ομότιμος Καθηγητής, Ιατρική, ΕΚΠΑ
Δημήτριος Κασσάνος, Ομότιμος Καθηγητής, Ιατρική, ΕΚΠΑ
Χαράλαμπος Χρέλιας, Αναπληρωτής Καθηγητής, Ιατρική, ΕΚΠΑ
Original Title:
Διαβήτης στην κύηση
Languages:
Greek
Translated title:
Gestational diabetes
Summary:
General part: Diabetes Mellitus (DM) is a metabolic disorder which is characterised by an abnormal increase of the concentration of the blood sugar. Concurrently, it can coexist with a disturbance of the lipid as well as protein metabolism. It can derive from an impaired pancreatic insulin secretion or can even be caused by a reduced sensitivity of the body cells to such hormone.
DM can be classified in type I and II and can be pre-gestational. The former can be treated by insulin administration whereas the latter can be initially controlled by dietetic adaptations, lifestyle changes and/or commencement of either insulin secretion promoting medications or hypoglycaemic agents, with insulin administration being the last resource.
With regards to the prevention, diagnosis and treatment of DM specific diagnostic tests can be performed in order to timely detect its systemic consequences (retinal disease, renal disease, vascular disease).
Scope: the scope of this thesis is the understanding as well as the prevention of all the events that lead to the development of DM in a previously healthy subject under the diabetogenic effect of the hormonal changes that are observed during gestation.
Special part: The gestational diabetes is a disturbance of the glucose tolerance with onset and first diagnosis during gestation. Regular monitoring of the gravid woman and of the fetus with specific investigations and appropriate control of her glycaemic profile mitigates the consequences for the mother on one hand and for the new-born on the other. Consequences for the mother include: preterm birth, miscarriage, pre-eclampsia, oedema, hypertension. Whereas consequences for the new-born include: traumatic injuries at delivery due to macrosomia, hypoglycemia and electrolyte disturbances.
What is more, the woman who has been diagnosed with gestational diabetes will come under a special monitoring protocol in order to plan further gestations with potential re-development of diabetes and in view of the high risk of developing Type II DM and obesity in the future, a risk that concerns not only the mother but the child as well, along its growth and adult life.
Conclusions: the timely diagnosis, prevention and appropriate treatment of gestational DM reduces perinatal morbidity and mortality on one hand and also decreases health care costs on the other.
Main subject category:
Health Sciences
Keywords:
Diabetes mellitus, Pregnancy, Neonatal complications
Index:
No
Number of index pages:
0
Contains images:
Yes
Number of references:
77
Number of pages:
135
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