Unit:
Κατεύθυνση Ορθοδοντική (Κλινικές Ειδικεύσεις)Βιβλιοθήκη Οδοντιατρικής
Supervisors info:
Δημήτριος Χαλαζωνίτης, Καθηγητής, Τμήμα Οδοντιατρικής, Σχολή Επιστημών Υγείας, ΕΚΠΑ
Απόστολος Τσολάκης, Αναπληρωτής Καθηγητής, Τμήμα Οδοντιατρικής, Σχολή Επιστημών Υγείας, ΕΚΠΑ
Ηλίας Μπιτσάνης, Επίκουρος Καθηγητής, Τμήμα Οδοντιατρικής, Σχολή Επιστημών Υγείας, ΕΚΠΑ
Original Title:
Μορφομετρική συσχέτιση του σχήματος του κρανιοπροσωπικού συμπλέγματος με την αναλογία του μήκους των δακτύλων (2Δ:4Δ) πριν και μετά την εφηβεία
Translated title:
Morphometric correlation of craniofacial shape and 2D:4D digit ratio before and after puberty
Summary:
2D:4D ratio follows a sexually dimorphic pattern; men tend to have a lower digit ratio than women, with overlap between male and female distribution. Lower digit ratio is associated with greater prenatal androgen stimulation in boys and characteristics more commonly displayed in males.2D:4D ratio has been suggested to be a marker of prenatal androgen levels in humans; this may affect the differentiation of many sex-dependent traits, such as the craniofacial shape, as well as the development of some behaviors and diseases. The aim of our study was to investigate if there is a correlation between this ratio and the craniofacial shape in pre- and post-pubertal subjects, using geometric morphometric analysis. Our sample was collected from the historic database of the Burlington Growth Study Collection and consisted of hand-wrist radiographs and cephalograms of 70 subjects at two time points; 36 boys at 10 (T1) and 18 (T2) years of age and 34 girls at 10(T1) and 17(T2) years of age. Digit ratio was estimated by digitized hand- wrist radiographs using computer software specifically configured, while the craniofacial shape was described by 15 continuous curves; Procrustes superimposition and PCA analysis described the shape variability of the craniofacial skeleton. The male digit ratio (2D:4D= 0,924032) was statistically significant smaller than the female ratio (2D:4D= 0,938945)(P=0,002). Craniofacial shape did not present sexual dimorphism before puberty and showed its sexually dimorphic pattern only post-pubertal. No statistically significant correlation was found between digit ratio and craniofacial shape at T1 for girls and boys (P=0,20 and P=0,32 respectively), neither at T2 (P=0.78 and P=0,80, respectively).
Main subject category:
Health Sciences
Keywords:
Morphometrics, Digit ratio, Craniofacial complex
