Obstructive Sleep Apnea and Bronchial Asthma

Postgraduate Thesis uoadl:2867507 326 Read counter

Unit:
Κατεύθυνση Διαταραχές της αναπνοής στον ύπνο - Εργαστηριακή και Κλινική Ιατρική του Ύπνου
Library of the School of Health Sciences
Deposit date:
2019-04-09
Year:
2019
Author:
Damianaki Angeliki
Supervisors info:
Κατσαούνου Παρασκευή, Επίκουρη Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Ζακυνθινός Σπυρίδων, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Λουτράρη Ελένη, ΕΔΙΠ, Ιατρική Σχολή, ΕΚΠΑ
Original Title:
Αποφρακτική Υπνική Άπνοια και Βρογχικό Άσθμα
Languages:
Greek
Translated title:
Obstructive Sleep Apnea and Bronchial Asthma
Summary:
Obstructive Sleep Apnea (OSA) and Bronchial Asthma (BA).
Introduction: OSA and BA are common respiratory diseases and consequently they may co-exist accidentally. The strength of this association and how much influences the two diseases, remain unknown. Until now, reviews focus chiefly on the epidemiology.
Objectives: the review of the international literature regarding the association of these diseases in relation to epidemiology, pathophysiology, consequences and therapy.
Material and methods: studies in English were selected from the PubMed data base from 1990 to 2018. Older studies were included whenever was necessary.
Results:
The majority of studies referred to asthmatic populations focusing on the prevalence of OSA. OSA prevalence in asthmatics is increased (19-50%) and depends on asthma duration and severity as well as on the increased dose of steroids. The two diseases seem to affect each other in terms of pathophysiology. In most studies OSA seems to deteriorate the BA outcome especially the exacerbations. C-pap treatment is likely to improve the control of the disease and quality of life in asthmatics with OSA, however almost all studies are observational ones, involving small number of patients and a short period of follow up.
Conclusions:
OSA prevalence is high enough in asthmatics mainly in those with severe BA and this suggests that the co-existence of the two diseases is not accidental. Co-diagnosis of OSA in asthma patients is associated with worse clinical outcomes. However large prospective studies with objective measurements of sleep and pulmonary function are needed to confirm a possible causative association between BA- OSA.
Main subject category:
Health Sciences
Keywords:
Obstructive sleep apnea, Bronchial asthma
Index:
No
Number of index pages:
0
Contains images:
Yes
Number of references:
171
Number of pages:
78
File:
File access is restricted only to the intranet of UoA.

ΑΓΓΕΛΙΚΗ ΔΑΜΙΑΝΑΚΗ- ΔΙΠΛΩΜΑΤΙΚΗ ΕΡΓΑΣΙΑ-ΑΠΟΦΡΑΚΤΙΚΗ ΥΠΝΙΚΗ ΑΠΝΟΙΑ ΚΑΙ ΒΡΟΓΧΙΚΟ ΑΣΘΜΑ.pdf
4 MB
File access is restricted only to the intranet of UoA.