Unit:
Library of the School of Health SciencesΠΜΣ Κλινική Εργοσπιρομετρία, Άσκηση και Αποκατάσταση
Supervisors info:
Ανδρέας Καραμπίνης, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Σεραφείμ Νανάς, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Ιωάννης Βασιλειάδης, Επίκουρος Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Original Title:
H κλινική και προγνωστική αξία της μυϊκής μάζας του τετρακεφάλου μυός σε ασθενείς μετά από καρδιοχειρουργική επέμβαση
Translated title:
Clinical and predictive value of quadriceps muscle in patients after cardiac surgery
Summary:
Patients undergoing cardiac surgery demonstrate muscular atrophy of the quadriceps muscle postoperatively. This appears to be associated with extended ICU stay as well as poor quality of life after their exit from the hospital. This thesis is a prospective clinical study. The aim of this study is to highlight the predictive value of quadriceps muscle mass in patients after cardiac surgery. In addition, we recorded the percentage of possible muscle atrophy in these patients directly postoperatively. We recorded the relationship between ICAW and ventilation as well as ICU length of stay.
According to the research protocol, patients who underwent on cardiac surgery and entered to the cardio surgical Intensive Care Unit (ICU) at the Onassis Cardiac Surgery Center, were enrolled to the study. Quadriceps muscle mass was measured using muscle ultrasound and muscle strength evaluated with MRC scale. The assessment for both parameters was repeated every 48 hours and completed within seven (7) days after the first evaluation or when exit from the ICU if this occurred in a period of less than 7 days. Moreover, physiotherapy intervention was recorded at the respective time intervals.
Using ultrasound as a diagnostic tool has allowed us to detect muscle mass loss in a direct and reliable way. Muscle ultrasound has emerged in recent years as a valuable tool for assessing the structure and quality of muscle mass.
The results of the study showed the relationship between clinical parameters of the study population. The loss of the quadriceps muscle mass during the first week of hospitalization in the ICU was notable. The relationship between muscle size and ICU stay as well as the relationship between ICUAW, ventilation and duration of extracorporeal circulation during surgery were noteworthy. The duration of ventilation, sedation and long term hospitalization were correlated to mortality. Another finding regarding physiotherapy intervention was that most of the patients that were mobilized had a better outcome and improved their health condition.
Main subject category:
Health Sciences
Keywords:
Intensive care unit-acquired weakness, Critical illness, Muscle atrophy, Skeletal muscle wasting, Muscle Ultrasound, Quadriceps femoris, Muscle thickness
