Correlations of polisomnografy parameter's with cardiac events

Postgraduate Thesis uoadl:2878225 308 Read counter

Unit:
Κατεύθυνση Διαταραχές της αναπνοής στον ύπνο - Εργαστηριακή και Κλινική Ιατρική του Ύπνου
Library of the School of Health Sciences
Deposit date:
2019-07-09
Year:
2019
Author:
Kavoura Paraskevi
Supervisors info:
Σπυρίδων Ζακυνθινός, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ, Επιβλέπων
Χριστίνα Ρούτση, Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Ελένη Λουτράρη, ΕΔΙΠ, Ιατρική Σχολή, ΕΚΠΑ
Original Title:
Συσχέτιση των παραμέτρων της μελέτης ύπνου με καρδιολογικά συμβάματα
Languages:
Greek
Translated title:
Correlations of polisomnografy parameter's with cardiac events
Summary:
Introduction: Obstructive Sleep Apnoea Syndrome (OSA) is a respiratory disorder characterized by recurrent airflow obstruction caused by total or partial collapse of the upper airway. It is estimated that 4% of men and 2% of women aged 30–60 years suffer from OSA. OSA is an established independent factor of cardiovascular risk together with other risk factors such as smoking and elevated lipids. Moreover, it is supposed to play an important role in arterial hypertension, although the relating mechanisms still remain unclear. Nocturnal hypoxia is characterized by a decrease in oxygen saturation during sleep. The oxygen desaturation index is used to estimate the severity of hypoxia.
The aim of this study was to assess if the TST, REM, ODI, min SpO2% and the min level of O2 could be risk factors for cardiovascular diseases in patients with OSA. Materials and methods: we studied 55 male and female 40-88-year-olds who went to sleep clinic at the Sotiria Hospital KAA to investigate a possible sleep disorder. Patient selection was based on past medical history, symptomatology and co-morbidity. Patients were divided into two groups. Both groups had OSA confirmed after polysomnografy.
The first group included patients with no known cardiac history and without medication. The number of participants in this group was 23 patients. The second group included 22 patients with a history of coronary artery disease, heart failure, arterial hypertension, arrhythmias and related treatment. TST, AHI,ODI, REM and min level of O2 were studied in both patient groups. Results: It has been shown that TST does not statistically affect the existence of cardiac events. Likewise, REM is not a predisposing factor for heart disease. Furthermore, the ODI, and the minimum level of O2 (min level O2) seems that does not represent predisposing factors for cardiac events manifestation. Conclusions: According to the findings of this study, there appears to not be a direct relationship between the desaturation of hemoglobin ,min level of O2, the sleep quality and the occurrence of cardiac events.
Main subject category:
Health Sciences
Keywords:
OSI, ODI, TST, min level of O2%, Cardiac events
Index:
No
Number of index pages:
0
Contains images:
Yes
Number of references:
257
Number of pages:
71
File:
File access is restricted only to the intranet of UoA.

ΣΥΣΧΕΤΙΣΗ ΠΑΡΑΜΕΤΡΩΝ ΤΟΥ ΥΠΝΟΥ ΜΕ ΚΑΡΔΙΟΛΟΓΙΚΑ ΣΥΜΒΑΜΑΤΑ-FINAL.22.05.19(3).pdf
1 MB
File access is restricted only to the intranet of UoA.