Κατεύθυνση Κλινική Νευροφυσιολογία
Library of the School of Health Sciences

2019-07-18

2019

Kazakou Maria

Νικόλαος Καρανδρέας, Ομότιμος Καθηγητής, Τμήμα Ιατρικής, Σχολή Επιστημών Υγείας, ΕΚΠΑ
Θωμάς Ζαμπέλης, Αναπληρωτής Καθηγητής, Τμήμα Ιατρικής, Σχολή Επιστημών Υγείας, ΕΚΠΑ
Παναγιώτης Κοκότης, Επίκουρος Καθηγητής, Τμήμα Ιατρικής, Σχολή Επιστημών Υγείας, ΕΚΠΑ

Καταγραφή του σύνθετου μυϊκού δυναμικού ενέργειας του βραχύ απαγωγού του αντίχειρα με υψιπερατό φίλτρο

Greek

The recording of the compound muscle action potential of the abductor pollicis brevis with high-pass filter

Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy. Although the confirmation of the clinical diagnosis is achieved through electrodiagnostic tests, there are still cases of CTS where these tests cannot show the dysfunction of the median nerve. It is commonly accepted that the sensory conduction of the median nerve is more sensitive than the motor during the electrodiagnosis of the syndrome. However, the parameters of the morphology of the peripheral compound muscle action potential (CMAP) seem promising for the diagnosis of the mild CTS. This study aims first, to measure the slope of the rising edge belonging to the abductor pollicis brevis CMAP’s negative peak and second, to correlate it with the parameters that are commonly used for the evaluation of the motor and sensory conduction of the median nerve. The study was performed on healthy subjects. The amplitude of the potential, which was measured in parallel with the CMAP using a bandpass filter of 1kHz10kHz, represents the first derivative of the CMAP. Hence, it was used as a representation of the slope. Data was evaluated from both hands of 50 healthy subjects and we have discovered that there is statistically significant correlation among the CMAP’s first amplitude (1kHz10kHz) and both amplitude and area of CMAP’s negative peak (10Hz-10kHz). Moreover, the amplitude of the CMAP’s first negative peak (1kHz-10kHz) is statically significantly correlated with the distal motor latency and with the sensory conduction velocity of the median nerve (carpal-second digit). Future work will concern the verification of the slope’s value in the research of the early stages of demyelination.

Health Sciences

Compound muscle action potential, Abductor pollicis brevis, High-pass filter, Carpal tunnel syndrome, Median nerve

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https://pergamos.lib.uoa.gr/uoa/dl/object/2879294