Type 2 Diabetes (T2D): Association between Clinical and Ophthalmological markers with clinical psychopathology and quality of life

Doctoral Dissertation uoadl:2881957 299 Read counter

Unit:
Τομέας Κοινωνικής Ιατρικής - Ψυχιατρικής και Νευρολογίας
Library of the School of Health Sciences
Deposit date:
2019-10-02
Year:
2019
Author:
Ligda Georgia
Dissertation committee:
Πλουμπίδης Δημήτριος, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Νικολάου Χρυσούλα, Καθηγήτρια Ιατρική Σχολή, ΕΚΠΑ, Επιβλέπουσα
Τεντολούρης Νικόλαος, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Μακρυλάκης Κωνσταντίνος, Αναπληρωτής Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Τζαβέλλας Ηλίας, Αναπληρωτής Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Χατζηπαναγιώτου Στυλιανός, Αναπληρωτής Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Κόκκινος Αλέξανδρος, Αναπληρωτής Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Original Title:
Σακχαρώδης Διαβήτης Τύπου 2: Σχέση βιοχημικών και οφθαλμολογικών δεικτών με κλινική ψυχοπαθολογία και ποιότητα ζωής
Languages:
Greek
Translated title:
Type 2 Diabetes (T2D): Association between Clinical and Ophthalmological markers with clinical psychopathology and quality of life
Summary:
Diabetes Mellitus (DM) and its consequences have a basic biological background that is related with complex psychological issues and physical and mental illnesses that affect many aspects of life (organic, intrapulmonary, individual and social). Its multifactorial nature makes it difficult to diagnose it at an early stage. The magnitude of the problem is recorded with the epidemic, longitudinal increase of the DM incidents. Moreover, morbidity and mortality due to the long-term vascular complications of DM are increased.
DM affects the patient and his family life. After the DM diagnosis, the patient should accept the new life in a new body that is ill. Blood sugar surplus is often present and related to emotional deadlocks, which are not only cured by insulin and medication.
The DM is a psychological burden that affects the quality of life of the patient. Mental disorders such as depression, anxiety, sexual dysfunction, low self-confidence and self-esteem, unpleasant feelings and behaviors such as denial, passivity for change, anxiety and frustration about life are often issues in diabetic patients. The emotional and social impact of DM can cause significant psychosocial dysfunction in patients. Particularly when diabetes is not regulated and controlled, it results in painful complications, one of which is Diabetic Retinopathy (DR), the main cause of blindness in adults. The eye is significantly affected and very early in the DM patients and the lesions affect almost the entire structure of the eye. As a complication of DM, DR is a social and psychological problem because of the increased probability of blindness. DR is the most common cause of blindness in the age of 30-60 years.
Acceptance of the disease and primary care can significantly help the patient to reduce the risk of vision loss, resulting in improved mental health and upgrading the quality of life.
The purpose of this study was to investigate the relationship of demographic characteristics, mental health, quality of life and well-being, clinical and laboratory measures between patients with type 2 diabetes who suffered from retinopathy in relation to patients with type 2 diabetes but without retinopathy comparing to with healthy controls.
The study included 70 patients with type 2 diabetes, 70 patients with type 2 diabetes and Diabetic Retinopathy and a group of 70 healthy individuals from the Diabetes Center of the Laiko Hospital of Athens. Also, the group of healthy individuals has the same age spectrum, gender and monthly family income with the groups of diabetic patients. This study showed that Quality of Life was significantly lower in people with Type 2 diabetes mellitus and DR than those without DR. DR has a significant impact on physical and mental health compared to people without DR. Patients with DM and DR have an increased level of depression and anxiety, reduced glycemic control, a reduced sense of subjective well-being that reflects a lower quality of life comparing to healthy individuals. In conclusion, quality of life of patients with type 2 diabetes mellitus is related to the satisfaction of their emotional needs. Analyzing data of the Psychopathology questionnaire it turned out that the degree of psychological burden is higher in people with DM than in non-diabetic patients. However, retinopathy does not cause further burden on people with DM.
Main subject category:
Health Sciences
Keywords:
Type 2 Diabetes Mellitus, Biochemical Indicators, Diabetic Retinopathy, Quality of Life, Psychopathology
Index:
No
Number of index pages:
0
Contains images:
Yes
Number of references:
129
Number of pages:
123
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