Current non-operative approach of locally advanced rectal cancer

Postgraduate Thesis uoadl:2884607 90 Read counter

Unit:
Κατεύθυνση Χειρουργική Ογκολογία
Library of the School of Health Sciences
Deposit date:
2019-11-02
Year:
2019
Author:
Kontopoulou Christina
Supervisors info:
Γεώργιος Πολυμενέας, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ, Επιβλέπων
Θεοδόσιος Θεοδοσόπουλος, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Κωνσταντίνος Γ. Τούτουζας, Αναπληρωτής Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Original Title:
Σύγχρονη μη χειρουργική προσέγγιση τοπικά προχωρημένου καρκίνου του ορθού
Languages:
Greek
Translated title:
Current non-operative approach of locally advanced rectal cancer
Summary:
The management of locally-advanced rectal cancer involves a combination of chemotherapy, chemoradiation, and surgical resection to provide excellent local tumor control and overall survival. However, aspects of this multimodality approach are associated with significant morbidity and long-term sequelae. In addition, there is growing evidence that patients with a clinical complete response to chemotherapy and chemoradiation treatments may be safely offered initial non-operative management in a rigorous surveillance program. Weighed against the morbidity and significant sequelae of rectal resection, recognizing how to best optimize non-operative strategies without compromising oncologic outcomes is critical to our understanding and treatment of this disease.
Main subject category:
Health Sciences
Keywords:
Locally advanced rectal cancer, Rectal MRI, Neoadjuvant chemoradiotherapy, Watch and Wait Strategy
Index:
No
Number of index pages:
0
Contains images:
Yes
Number of references:
75
Number of pages:
36
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