Unit:
Κατεύθυνση Ορθοδοντική (Κλινικές Ειδικεύσεις)Βιβλιοθήκη Οδοντιατρικής
Supervisors info:
Ιωσήφ Σηφακάκης, Επίκουρος Καθηγητής, Tμήμα Oδοντιατρικής, Σχολή Επιστημών Υγείας, ΕΚΠΑ
Δημήτριος Χαλαζωνίτης, Καθηγητής, Tμήμα Oδοντιατρικής, Σχολή Επιστημών Υγείας, ΕΚΠΑ
Αναστασία Μητσέα, Επίκουρη Καθηγήτρια, Tμήμα Oδοντιατρικής, Σχολή Επιστημών Υγείας, ΕΚΠΑ
Original Title:
Craniofacial shape in patients with beta thalassemia: A morphometric analysis
Translated title:
Craniofacial shape in patients with beta thalassemia: A morphometric analysis
Summary:
AIM: To morphometrically evaluate the shape of the craniofacial complex of patients with betathalassemia and compare it with matched controls.MATERIALS AND METHOD: Beta thalassemia group consisted of 40 patients (16 females, 24 males). Each patient was matched on age and gender to two controls (n=80 controls). A total of 120 lateral cephalometric radiographs were collected, one from each patient, digitized and traced with 15 curves and 127 semi-landmarks. These landmarks were subjected to Procrustes superimposition and principal component analysis in order to describe shape variability of the cranial base, maxilla and mandible, as well as of the entire craniofacial complex for each sex. Error of the method was evaluated using both an intra-and inter observer approach.RESULTS: The beta thalassemia group was significantly different in shape to the control group for both sexes (P<0.001). The groups were clearly separated in shape space. The main differences were related to smaller mandibular body for the thalassemia group, midface protrusion and decrease in posterior face height. These shape differences are in accordance with the well known clinical and radiological characteristics of this disease.
Main subject category:
Health Sciences
Keywords:
Beta thalassaimia, Morphometrics, Orthodontics, Craniofacial complex
