Unit:
Κατεύθυνση Εργαστηριακή / Βασική ΈρευναLibrary of the School of Health Sciences
Author:
Thgana Paraskevoula
Supervisors info:
Κλειώ Μαυραγάνη, Αναπληρώτρια Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Μιχάλης Κουτσιλιέρης, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Γεώργιος Βαϊόπουλος, Ομότιμος Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Original Title:
Ο ρόλος των αυτοαντισωμάτων στο συστηματικό σκληρόδερμα (SSc). Νεότερες εξελίξεις και προοπτικές
Translated title:
The role of autoantibodies in systemic sclerosis (SSc).Latest developments and future prospects
Summary:
Systemic sclerosis (SSc) is an autoimmune disease with symptoms such as fibrosis of the skin and the internal organs, vasculopathy, and dysregulation of the immune system. In recent years, the presence of antinuclear antibodies which are detected in up to 90-95% of patients with SSc through various laboratory methods, is a diagnostically important feature of immunological abnormalities in SSc. There are up to 10 antinuclear antibodies specific to SSc and all of them are linked to distinct clinical features. Therefore, detecting a specific antibody type is really important in predicting a possible organ involvement and improving prognosis, monitoring and treatment of the disease.
Main subject category:
Health Sciences
Keywords:
Antinuclear antibodies, Prognosis, Scleroderma, Systemic sclerosis
