Association of endometriosis and breast cancer

Postgraduate Thesis uoadl:2920737 161 Read counter

Unit:
Κατεύθυνση Έρευνα στην Γυναικεία Αναπαραγωγή
Library of the School of Health Sciences
Deposit date:
2020-07-29
Year:
2020
Author:
Anyfantaki Foteini
Supervisors info:
Σαλάκος Νικόλαος, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ, Επιβλέπων
Πανουλής Κωνσταντίνος, Αναπληρωτής Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Καλαμπόκας Θεόδωρος, Πανεπιστημιακός Υπότροφος, Ιατρική Σχολή, ΕΚΠΑ
Original Title:
Συσχέτιση ενδομητρίωσης και καρκίνου μαστού
Languages:
Greek
Translated title:
Association of endometriosis and breast cancer
Summary:
Background: Endometriosis is a common, estrogen-dependent, gynecological disease, which is defined as the presence of endometrial tissue outside the uterine cavity. Current data have associated endometriosis with specific malignancies, including ovarian and breast cancer.
Purpose: The purpose of this study is to summarize and present published literature providing evidence regarding the possible relationship between endometriosis and breast cancer.
Methods: Pubmed and Scopus databases were searched systematically for studies that sought to identify a potential association of endometriosis and breast cancer. 15 relevant articles were retrieved and included in the present review.
Results: A small number of observational studies have shown a correlation of endometriosis and breast cancer. The scenario of an early interruption of the inflammatory process, derived from endometriosis, by oophorectomy and a possible consequent decrease in the risk of breast cancer has also been proposed. The hypothesis that both conditions could be related through common mutations on BRAC1 and BRAC2 genes has also been investigated.
Conclusion: The available published evidence is inconclusive. Further studies are needed to evaluate the association of endometriosis and breast cancer and the possible pathogenetic pathways that relate the two disorders.
Main subject category:
Health Sciences
Keywords:
Endometriosis, Breast cancer
Index:
No
Number of index pages:
0
Contains images:
Yes
Number of references:
42
Number of pages:
41
File:
File access is restricted only to the intranet of UoA.

ΜΕΤΑΠΤΥΧΙΑΚΟ-ανυφαντακη.pdf
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