Preliminary Study of Dosimetric Parameters in CT Simulation in Radiation Therapy Within the Framework of the Optimization Principle

Postgraduate Thesis uoadl:2925374 139 Read counter

Unit:
Κατεύθυνση Ιατρική Φυσική-Ακτινοφυσική
Library of the School of Health Sciences
Deposit date:
2020-10-26
Year:
2020
Author:
Lamprinos Michail
Supervisors info:
Εμμανουήλ Παπαναστασίου, Επίκουρος Καθηγητής, Ιατρική Σχολή, Α.Π.Θ.
Αναστάσιος Σιούντας, Καθηγητής, Ιατρική Σχολή, Α.Π.Θ.
Παναγιώτης Μπαμίδης, Καθηγητής, Ιατρική Σχολή, Α.Π.Θ.
Original Title:
Προκαταρτική Μελέτη Δοσιμετρικών Παραμέτρων Αξονικής Τομογραφίας Προσομοίωσης Στην Ακτινοθεραπεία Στα Πλαίσια Της Αρχής Της Βελτιστοποίησης
Languages:
Greek
Translated title:
Preliminary Study of Dosimetric Parameters in CT Simulation in Radiation Therapy Within the Framework of the Optimization Principle
Summary:
More than 50% of the patients with cancer worldwide, will receive Radiotherapy at some point in their treatment. Radiotherapy is a fundamental pillar in the treatment of various types of cancer like breast cancer, prostate cancer, lung cancer, head & neck cancer, and cervical cancer.
The contribution of CT Simulation process in the whole treatment is quite important, due to the fact that the generated 3D images contain all the necessary information regarding the simulation and verification process for the treatment plan. However, the patient receives a relatively high dose. Therefore the reduction of this dose is essential in terms of optimization.
Based on the optimization principle, the scope of this study was the analysis/exploration of different dosimetric and technical features from generated images in CT Simulation process.
The sample of the study was consisted of 165 patients with various types of cancer, receiving Radiotherapy. The data were collected from CT Simulator GE RT LightSpeed, which is used at the Radiotherapy department of AHEPA General University Hospital of Thessaloniki. Data were also collected from the specialized treatment planning software Monaco and Eclipse.
After analyzing and exploring the data, the main conclusion that was conducted from this study, based on the optimization principle, was that there are two possible ways to reduce patient’s dose: i.) by reducing CTDI_vol parameter or ii.) by reducing total scan length. The first way is not easy as it requires time and long clinical experience. The second way is easier and faster.
Main subject category:
Health Sciences
Keywords:
Radiotherapy, CT simulation, Organ dose, Optimization principle
Index:
No
Number of index pages:
0
Contains images:
Yes
Number of references:
58
Number of pages:
119
File:
File access is restricted only to the intranet of UoA.

Λαμπρινός Ι. Μιχαήλ.pdf
5 MB
File access is restricted only to the intranet of UoA.