Unit:
Κατεύθυνση Αποκατάσταση Βλαβών Νωτιαίου Μυελού. Διαχείριση του πόνου Σπονδυλικής προέλευσηςLibrary of the School of Health Sciences
Supervisors info:
Ελευθερία-Μαρία Ευαγγελοπούλου, Επίκουρη Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Ιωάννης Βλάμης, Επίκουρος Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Δημήτριος-Στέργιος Ευαγγελόπουλος, Ακαδημαϊκός Υπότροφος, Ιατρική Σχολή, ΕΚΠΑ
Original Title:
Η αντίδραση της μικρογλοίας στη βλάβη του νωτιαίου μυελού
Translated title:
Microglia reaction after spinal cord Injury
Summary:
Microglial cells are endogenous immune cells of the central nervous system (CNS) and are involved in immune surveillance, defense and maintenance of homeostasis within it, under normal conditions. However, in the event of a spinal cord injury, the microglial cells respond differently. This reaction of microglial cells is dual in nature and greatly affects the progression of the injury. Microglial cells perform important functions in spinal cord injury and their distinct roles have been described more accurately in recent years. They elicit a non-specific immune response that can aggravate any damage, but are also necessary for spinal cord repair and restoration. The present review of the recent literature describes the reaction of microglia after spinal cord injury, the specific beneficial or harmful functions it performs as well as the interaction of microglia cells with other cells in the area of the lesion.
Main subject category:
Health Sciences
Keywords:
Microglial cells, Microglia, Spinal cord injury
