The Effect of Spinal Cord Epidural Stimulation on the Recovery of Individuals with Spinal Cord Injury

Postgraduate Thesis uoadl:2928637 10 Read counter

Κατεύθυνση Αποκατάσταση Βλαβών Νωτιαίου Μυελού. Διαχείριση του πόνου Σπονδυλικής προέλευσης
Library of the School of Health Sciences
Deposit date:
Verigaki Despoina
Supervisors info:
Ευαγγελοπούλου Ελευθερία-Μαρία, Επίκουρη Καθηγήτρια, Ιατρική Σχολή Ε.Κ.Π.Α
Βλαμης Ιωάννης, Επίκουρος Καθηγητής, Ιατρική Σχολή Ε.Κ.Π.Α
Ευαγγελοπουλος Δημήτριος-Στεργιος Ακαδημαϊκός Υπότροφος, Ιατρική σχολή Ε.Κ.Π.Α
Original Title:
Επίπτωση της επισκληρίδιας διέγερσης στη βελτίωση της αποκατάστασης ασθενών με βλάβη νωτιαίου μυελού
Translated title:
The Effect of Spinal Cord Epidural Stimulation on the Recovery of Individuals with Spinal Cord Injury
Spinal Cord Injury (SCI) is a devastating condition, impairing the motor and sensory function below the level of injury and often leads to permanent neurological deficits. Although, there are no pharmacologic therapies for SCI, spontaneous neurologic recovery can occur depending on the severity of SCI, patient’s age and general health condition. The activity-dependent plasticity and the evidence of spared descending pathways below the level of injury may facilitate the functional recovery. Locomotor training has proved effective on functional recovery after SCI. However, locomotor training alone did not achieve significant improvement in motor function of patients with motor complete SCI. The combination of activity-based training with spinal cord epidural stimulation is a new approach leading to encouraging results for the recovery of full-weight bearing standing, over-ground walking and voluntary control of the lower limbs in motor complete SCI individuals. This review focused on individuals with motor complete SCI, classifies as AIS Grade A or AIS Grade B, because the prognosis for recovery of motor function is poor compared to incomplete SCI.
Main subject category:
Health Sciences
Spinal cord injury, Locomotor training, Epidural stimulation, Activity-based training
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