Κατεύθυνση Καρδιοαναπνευστική ΑναζωογόνησηLibrary of the School of Health Sciences
Ιακωβίδου Νικολέττα, Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Ξάνθος Θεόδωρος, Καθηγητής, Ευρωπαϊκό Πανεπιστήμιο Κύπρου
Χαλκιάς Αθανάσιος, Επίκουρος Καθηγητής, Ιατρική Σχολή, Πανεπιστήμιο Θεσσαλίας
Οι θυρεοειδικές ορμόνες στην ανακοπή: βιβλιογραφική ανασκόπηση
The role of thyroid hormones in cardiopulmonary resuscitation: a systematic review
Introduction: various pathophysiological changes occur during cardiac arrest (CA). One of these is the alteration in normal thyroid homeostasis. The purpose of this study is to review current literature and those clinical studies that analyze the role of thyroid hormone changes during cardiac arrest.
Materials and methods: we systematically searched Pubmed, the Cochrane Library and Google Scholar. Randomized control trials, observational studies and experimental studies were selected.
Results: our search initially identified 877 studies. Of them, 3 observational studies and 4 experimental studies met the inclusion criteria. No randomized control trials concerning the role of thyroid hormones during cardiopulmonary resuscitation were found in our research. During CA, changes in thyroid homeostasis occur that appear to be attributed to a low T3 syndrome.
Conclusions: based on existing literature, significant changes in thyroid hormone levels occur during CA. The usefulness of this conclusion is that thyroid hormones could be a predictive biomarker for CA victims and that they could be used therapeutically, helping to improve life expectancy. Further research and, even, randomized, double-blind studies are needed in order to reach safe conclusions regarding the role of thyroid hormones in CA.
Keywords: cardiac arrest; cardiopulmonary resuscitation; thyroid hormones; thyroxine; review
Main subject category:
Cardiac arrest; Cardiopulmonary resuscitation; Thyroid hormones; Thyroxine; Triiodothyronine; Review
Number of references:
Diamantopoulou Eleni-Varvara Master.pdf
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