Unit:
Specialty NanomedicineLibrary of the School of Health Sciences
Supervisors info:
Γαζούλη Μαρία, Αναπληρώτρια Καθηγήτρια, Τμήμα Ιατρικής, ΕΚΠΑ, Επιβλέπουσα
Κατηφελής Έκτωρ, Διδάκτωρ, Εργαστήριο Βιολογίας, Τμήμα Ιατρικής, ΕΚΠΑ
Πίππα Νατάσα, Διδάκτωρ, Εργαστήριο Φαρμακευτικής Νανοτεχνολογίας, Τμήμα Φαρμακευτικής, ΕΚΠΑ
Original Title:
Nano-NSAIDs & Cancer: A novel approach for commonplace drugs in oncology practice
Translated title:
Nano-NSAIDs & Cancer: A novel approach for commonplace drugs in oncology practice
Summary:
Nonsteroidal anti-inflammatory drugs (NSAIDs) are a class of drugs that are amongst the most commonly prescribed drugs on a global scale. NSAIDs are widely known for their activity against inflammation, as well as for their antipyretic and analgesic properties. NSAIDs have been extensively studied for their chemotherapeutic and chemopreventive activity against various types of cancer, underlining their capacity as a commonplace, off-the-shelf anti-tumor agent. The last years have seen a great increase in the use of nanotechnology in modern medicine, especially due to the unique properties of nanoparticles. These properties include their much smaller size, greater surface area and many other unparalleled chemical, optical, and electrical properties. The full anticancer potential of nonsteroidal anti-inflammatory drugs on the nano scale has not been exploited and, for the most part, remains unrealized. This review aims to shed a light on the use of nano-NSAIDs in cancer treatment, suggest future courses of action, and hopefully inspire future research in order to expand current knowledge on the unexplored potential of nano-NSAIDs in chemotherapy.
Main subject category:
Health Sciences
Keywords:
NSAIDs, Non-steroidal anti-inflammatory drugs, Nanotechnology, Cancer, Oncology
Number of references:
144
